Gastric cancer pathology and underlying molecular mechanisms
HI Grabsch, P Tan - Digestive surgery, 2013 - karger.com
The development of gastric adenocarcinoma is a complex multistep process involving
multiple genetic alterations. Based on pathology, four different macroscopic types and at …
multiple genetic alterations. Based on pathology, four different macroscopic types and at …
A pan-cancer proteomic perspective on The Cancer Genome Atlas
Protein levels and function are poorly predicted by genomic and transcriptomic analysis of
patient tumours. Therefore, direct study of the functional proteome has the potential to …
patient tumours. Therefore, direct study of the functional proteome has the potential to …
[HTML][HTML] Challenges of deciphering gastric cancer heterogeneity
P Hudler - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Gastric cancer is in decline in most developed countries; however, it still accounts for a
notable fraction of global mortality and morbidity related to cancer. High-throughput methods …
notable fraction of global mortality and morbidity related to cancer. High-throughput methods …
Gene expression signature–based prognostic risk score in gastric cancer
JY Cho, JY Lim, JH Cheong, YY Park, SL Yoon… - Clinical cancer …, 2011 - AACR
Purpose: Despite continual efforts to develop a prognostic model of gastric cancer by using
clinical and pathologic parameters, a clinical test that can discriminate patients with good …
clinical and pathologic parameters, a clinical test that can discriminate patients with good …
Identification of genes with a correlation between copy number and expression in gastric cancer
Background To elucidate gene expression associated with copy number changes, we
performed a genome-wide copy number and expression microarray analysis of 25 pairs of …
performed a genome-wide copy number and expression microarray analysis of 25 pairs of …
Genome-wide gene copy number and expression analysis of primary gastric tumors and gastric cancer cell lines
S Junnila, A Kokkola, ML Karjalainen-Lindsberg… - BMC cancer, 2010 - Springer
Background Gastric cancer is one of the most common malignancies worldwide and the
second most common cause of cancer related death. Gene copy number alterations play an …
second most common cause of cancer related death. Gene copy number alterations play an …
Gene expression analysis identifies over‐expression of CXCL1, SPARC, SPP1, and SULF1 in gastric cancer
S Junnila, A Kokkola, T Mizuguchi… - Genes …, 2010 - Wiley Online Library
To elucidate gene expression signatures associated with gastric carcinogenesis, we
performed a genome‐wide expression analysis of 46 Finnish and 20 Japanese gastric …
performed a genome‐wide expression analysis of 46 Finnish and 20 Japanese gastric …
WGCNA identification of TLR7 as a novel diagnostic biomarker, progression and prognostic indicator, and immunotherapeutic target for stomach adenocarcinoma
Q Yuan, Q Zhou, J Ren, G Wang, C Yin… - Cancer …, 2021 - Wiley Online Library
Stomach adenocarcinoma (STAD) is a malignant tumor with high histological heterogeneity.
However, the potential mechanism of STAD tumorigenesis remains to be elucidated. The …
However, the potential mechanism of STAD tumorigenesis remains to be elucidated. The …
Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer
F Hosoda, Y Arai, N Okada, H Shimizu, M Miyamoto… - Oncogene, 2015 - nature.com
Chromosomal abnormalities are good guideposts when hunting for cancer-related genes.
We analyzed copy number alterations of 163 primary gastric cancers using array-based …
We analyzed copy number alterations of 163 primary gastric cancers using array-based …
Krüppel‐like factor 12 plays a significant role in poorly differentiated gastric cancer progression
Y Nakamura, T Migita, F Hosoda… - … journal of cancer, 2009 - Wiley Online Library
Gastric cancer is the second common malignant neoplasia in Japan, and its poorly
differentiated form is a deadly disease. To identify novel candidate oncogenes contributing …
differentiated form is a deadly disease. To identify novel candidate oncogenes contributing …