The nuclear lamina is an important structural determinant for the nuclear envelope as a
whole, attaching chromatin domains to the nuclear periphery and localizing some nuclear …

The linker of nucleoskeleton and cytoskeleton (LINC) complex, composed of outer and inner
nuclear membrane Klarsicht, ANC-1, and Syne homology (KASH) and Sad1 and UNC-84 …

The nuclear envelope defines the barrier between the nucleus and cytoplasm and features
inner and outer membranes separated by a perinuclear space (PNS). The inner nuclear …

Linker of nucleoskeleton and cytoskeleton (LINC) complexes span the nuclear envelope
and are composed of KASH and SUN proteins residing in the outer and inner nuclear …

The nuclear envelope links the cytoskeleton to structural components of the nucleus. It
functions to coordinate nuclear migration and anchorage, organize chromatin, and aid …

Many nuclear proteins form lamin-dependent complexes, including LEM-domain proteins,
nesprins and SUN-domain proteins. These complexes have roles in chromatin organization …

Nuclear migration and positioning within cells are critical for many developmental processes
and are governed by the cytoskeletal network. Although mechanisms of nuclear-cytoskeletal …

It has been demonstrated that nuclear lamins are important proteins in maintaining cellular
as well as nuclear integrity, and in maintaining chromatin organization in the nucleus …

Mechanical properties of the nuclear envelope have implications for cell and nuclear
architecture as well as gene regulation. Using isolated Xenopus oocyte nuclei, we have …

Nucleocytoplasmic coupling is mediated by outer nuclear membrane (ONM) nesprin
proteins and inner nuclear membrane Sun proteins. Interactions spanning the perinuclear …