Chemistry with [18F]Fluoride Ion

L Cai, S Lu, VW Pike - European Journal of Organic Chemistry, 2008 - Wiley Online Library
The success of molecular imaging with positron‐emission tomography (PET) depends on
the availability of selective molecular probes labeled with positron‐emitters, such asfluorine …

Initial and subsequent approach for the synthesis of 18FDG

JS Fowler, T Ido - Seminars in nuclear medicine, 2002 - Elsevier
2-deoxy-2-[18F] fluoro-d-glucose (18FDG) was developed in 1976 in a collaboration
between scientists at the National Institutes of Health, the University of Pennsylvania, and …

Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors

AA Wilson, A Garcia, J Parkes, P McCormick… - Nuclear medicine and …, 2008 - Elsevier
INTRODUCTION: A novel [18F]-radiolabelled phenoxyanilide,[18F]-FEPPA, has been
synthesized and evaluated, in vitro and ex vivo, as a potential positron emission tomography …

Neither azeotropic drying, nor base nor other additives: a minimalist approach to 18 F-labeling

R Richarz, P Krapf, F Zarrad, EA Urusova… - Organic & …, 2014 - pubs.rsc.org
A novel, efficient, time-saving and reliable radiolabeling procedure via nucleophilic
substitution with [18F] fluoride is described. Different radiolabeled aliphatic and aromatic …

Decreased hippocampal 5-HT2A receptor binding in major depressive disorder: in vivo measurement with [18F] altanserin positron emission tomography

MA Mintun, YI Sheline, SM Moerlein, AG Vlassenko… - Biological …, 2004 - Elsevier
BACKGROUND: Serotonin 5-HT2A receptors play an important role in the regulation of
many functions that are disturbed in patients with major depressive disorder. Postmortem …

Recommendations for fluorine-18 production

M Guillaume, A Luxen, B Nebeling, M Argentini… - International journal of …, 1991 - Elsevier
Data for the production of fluorine-18 (t 1/2= 109.6 min; β+= 100%) are reviewed. The
experience of some well-established European centres for positron emission tomography …

Chemistry of β +-Emitting Compounds Based on Fluorine-18

MC Lasne, C Perrio, J Rouden, L Barré… - Contrast Agents II …, 2002 - Springer
Positron emission tomography (PET) is a non-invasive imaging technology which provides a
unique window on the physiology and function of living organisms. It uses short-lived …

[PDF][PDF] PET tracers and radiochemistry

DJ Schlyer - ANNALS-ACADEMY OF MEDICINE SINGAPORE, 2004 - annals.edu.sg
This paper provides a brief review of the radiochemistry of radiopharmaceuticals used in
positron emission tomography (PET). It includes some history of PET, the basic formation of …

Fluorine-18 labeling methods: features and possibilities of basic reactions

HH Coenen - PET Chemistry: The driving force in molecular imaging, 2007 - Springer
Many experimental and established tracers make fluorine-18 the most widely used
radionuclide in positron emission tomography with an increasing demand for new or simpler …

Analysis of blood clearance and labeled metabolites for the estrogen receptor tracer [F-18]-16α-Fluorestradiol (FES)

DA Mankoff, TJ Tewson, JF Eary - Nuclear medicine and biology, 1997 - Elsevier
[F-18] 16α-Fluoroestradiol (FES) has been shown to be a tracer of estrogen receptor content
in breast tumors; however, quantitative analysis of FES images is complicated by the rapid …