Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the
importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health …

Comorbid mental disorders in subjects at clinical high risk for psychosis (CHR-P) may
impact preventive care. We conducted a PRISMA/MOOSE-compliant systematic meta …

Preventive approaches have latterly gained traction for improving mental health in young
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …

Bipolar disorder is heterogeneous in phenomenology, illness trajectory, and response to
treatment. Despite evidence for the efficacy of multimodality interventions, the majority of …

In psychiatry, there has been a growing focus on identifying at-risk populations. For
schizophrenia, these efforts have led to the development of early recognition and …

Aim The aim of the present study was to detect factors associated with duration of untreated
illness (DUI) in bipolar disorder (BD). Method A total of 1575 patients were selected for the …

Introduction No systematic review has estimated the consistency and the magnitude of the
risk of developing bipolar disorder I-II (BD-I/II) in individuals at clinical high risk for bipolar …

Background Early detection of prodromal symptoms may contribute to improving the
prognosis of patients with bipolar disorder (BD). The main objective of this systematic review …

Background After the existence of a bipolar disorder (BD) prodrome was established, the
development of clinical rating instruments has become relevant that are sufficiently brief to …

Bipolar disorder (BD) is a major mental disorder that significantly impairs behavior and
social functioning. This study assessed the network structure of prodromal symptoms in …