Cancer development is highly associated to the physiological state of the tumor
microenvironment (TME). Despite the existing heterogeneity of tumors from the same or from …

Drug screening—ie, testing the effects of a number of drugs in multiple cell lines—is used for
drug discovery and development, and can also be performed to evaluate the heterogeneity …

Bioprinting is a method by which a cell-encapsulating bioink is patterned to create complex
tissue architectures. Given the potential impact of this technology on neural research, we …

In the body, cells inhabit within a complex three-dimensional (3D) extracellular matrix that
provides physical and chemical signals to regulate the cell fate. Cultured cells in Petri dishes …

Neutrophils are the most abundant type of leukocytes in the blood, traditionally regarded as
the first immune responders to infections and inflammations. In the context of tumors …

The tumor microenvironment and its contribution to tumorigenesis has been a focal highlight
in recent years. A two-way communication between the tumor and the surrounding …

Background Whatever the target of an experiment in cell biology, cell counting and viability
assessment are always computed. The Trypan Blue (TB) assay was proposed about a …

Despite significant achievements in the understanding and treatment of cancer, it remains a
major burden. Traditional therapeutic approaches based on the 'one-size-fits-all'paradigm …

Introduction: Despite the increasing financial outlay on cancer research and drug discovery,
many advanced cancers remain incurable. One possible strategy for increasing the approval …

Conventional in vitro cancer models do not accurately reproduce the tumor
microenvironment (TME), so three-dimensional (3D)-bioprinting represents an excellent tool …