Background Exercise changes the concentrations of many metabolites, which are small
molecules (< 1.5 kDa) metabolized by the reactions of human metabolism. In recent years …

Physical activity (PA) and exercise are among the most important determinants of health.
However, PA is a complex and heterogeneous behavior and the biological mechanisms …

Background Metabolomics is a field of omics science that involves the comprehensive
measurement of small metabolites in biological samples. It is increasingly being used to …

Biomarkers are the measurable changes associated with physiological or
pathophysiological processes. Urine, unlike blood, lacks mechanisms for maintaining …

Dynamic changes in circulating and tissue metabolites and lipids occur in response to
exercise-induced cellular and whole-body energy demands to maintain metabolic …

Background Exposure to disinfection by-products (DBPs) in drinking water and chlorinated
swimming pools are associated with adverse health outcomes, but biological mechanisms …

Maternal age is a risk factor for congenital heart disease even in the absence of any
chromosomal abnormality in the newborn,,,,,,. Whether the basis of this risk resides with the …

Background Endurance exercise training, especially the high-intensity training, exhibits a
strong influence on the immune system. However, the mechanisms underpinning the …

Background Exercise modality differentially alters body composition and physical
performance. Metabolic changes underlying these outcomes can be tracked through …

An integrated analysis of gut microbiota, blood biochemical and metabolome in 52
endurance horses was performed. Clustering by gut microbiota revealed the existence of …