Uveal melanoma (UM) and retinoblastoma (RB), which cause blindness and even death,
are the most frequently observed primary intraocular malignancies in adults and children …

Background Compared with adult cancers, pediatric cancers are uniquely characterized by
a genomically stable landscape and lower tumor mutational burden. Alternative splicing …

Retinoblastoma (RB) is a cancer that forms in the developing retina of babies and toddlers.
The goal of therapy is to cure the tumor, save the eye and maximize vision. However, it is …

Retinoblastoma is a retinal cancer that affects children and is the most prevalent intraocular
tumor worldwide. Despite tremendous breakthroughs in our understanding of the …

Background Long non-coding RNA (lncRNA) as a widespread and pivotal epigenetic
molecule participates in the occurrence and progression of malignant tumors. DRAIC, a kind …

Retinoblastoma is a childhood retinal tumour that is the most common primary malignant
intraocular tumour. However, it has been challenging to identify the cell types associated …

Retinoblastoma (RB) is the most common pediatric intraocular malignancy and is a serious
vision-and life-threatening disease. The biallelic mutation of the retinoblastoma gene RB1 is …

Summary Glypican 2 (GPC2) is a MYCN-regulated, differentially expressed cell-surface
oncoprotein and target for immune-based therapies in neuroblastoma. Here, we build on …

Long non-coding RNA (lncRNA) is a subtype of noncoding RNA that has more than 200
nucleotides. Numerous studies have confirmed that lncRNA is relevant during multiple …

Retinoblastoma (RB) is the commonest malignant tumor of the infant retina. Besides genetic
changes, epigenetic events are also considered to implicate the occurrence of RB. This …