Virulence Factors of Pseudomonas Aeruginosa and Antivirulence Strategies to Combat Its Drug Resistance
C Liao, X Huang, Q Wang, D Yao, W Lu - Frontiers in cellular and …, 2022 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen causing nosocomial infections in
severely ill and immunocompromised patients. Ubiquitously disseminated in the …
severely ill and immunocompromised patients. Ubiquitously disseminated in the …
Ebselen and analogues: Pharmacological properties and synthetic strategies for their preparation
C Santi, C Scimmi, L Sancineto - Molecules, 2021 - mdpi.com
Ebselen is the leader of selenorganic compounds, and starting from its identification as
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
Regulation of biofilm exopolysaccharide production by cyclic di-guanosine monophosphate
MB Poulin, LL Kuperman - Frontiers in Microbiology, 2021 - frontiersin.org
Many bacterial species in nature possess the ability to transition into a sessile lifestyle and
aggregate into cohesive colonies, known as biofilms. Within a biofilm, bacterial cells are …
aggregate into cohesive colonies, known as biofilms. Within a biofilm, bacterial cells are …
Repurposing high-throughput screening identifies unconventional drugs with antibacterial and antibiofilm activities against Pseudomonas aeruginosa under …
G Di Bonaventura, V Lupetti, A Di Giulio… - Microbiology …, 2023 - Am Soc Microbiol
Pseudomonas aeruginosa is the most common pathogen infecting cystic fibrosis (CF) lungs,
causing acute and chronic infections. Intrinsic and acquired antibiotic resistance allow P …
causing acute and chronic infections. Intrinsic and acquired antibiotic resistance allow P …
Advances in pulmonary drug delivery targeting microbial biofilms in respiratory diseases
The increasing burden of respiratory diseases caused by microbial infections poses an
immense threat to global health. This review focuses on the various types of biofilms that …
immense threat to global health. This review focuses on the various types of biofilms that …
Antibacterial activity of ebselen
M Maślanka, A Mucha - International Journal of Molecular Sciences, 2023 - mdpi.com
Ebselen is a low-molecular-weight organoselenium compound that has been broadly
studied for its antioxidant, anti-inflammatory, and cytoprotective properties. These …
studied for its antioxidant, anti-inflammatory, and cytoprotective properties. These …
Ebselen: A Promising Repurposing Drug to Treat Infections Caused by Multidrug‐Resistant Microorganisms
A Alves de Lima e Silva… - … Perspectives on Infectious …, 2024 - Wiley Online Library
Bacterial multiresistance to drugs is a rapidly growing global phenomenon. New resistance
mechanisms have been described in different bacterial pathogens, threatening the effective …
mechanisms have been described in different bacterial pathogens, threatening the effective …
Ebselen: A Review on its Synthesis, Derivatives, Anticancer Efficacy and Utility in Combating SARS-COV-2
Ebselen is a selenoorganic chiral compound with antioxidant properties comparable to
glutathione peroxidase. It is also known as 2-phenyl-1, 2-benzisoselenazol-3 (2H)-one. In …
glutathione peroxidase. It is also known as 2-phenyl-1, 2-benzisoselenazol-3 (2H)-one. In …
Biofilm inhibition/eradication: exploring strategies and confronting challenges in combatting biofilm
A Srivastava, N Verma, V Kumar, P Apoorva… - Archives of …, 2024 - Springer
Biofilms are complex communities of microorganisms enclosed in a self-produced
extracellular matrix, posing a significant threat to different sectors, including healthcare and …
extracellular matrix, posing a significant threat to different sectors, including healthcare and …
Sterically hindered phenolic derivatives: effect on the production of Pseudomonas aeruginosa virulence factors, high-throughput virtual screening and ADME …
MY Gvozdev, IS Turomsha, VV Savich… - Archives of …, 2024 - Springer
Inhibition of quorum sensing is considered to be an effective strategy of control and
treatment of a wide range of acute and persistent infections. Pseudomonas aeruginosa is an …
treatment of a wide range of acute and persistent infections. Pseudomonas aeruginosa is an …