Colorectal cancer is common. As many patients present with advanced disease, an effective
screening test would have substantial clinical benefits. Recent progress in understanding …

Colorectal cancer (CRC) is among the most common malignancies and remains a major
cause of cancer-related death worldwide. Despite recent advances in surgical and …

Acommon question in clinical consultations is:“For this person, what are the likely effects of
one treatment compared with another?” The central tenet of evidence based medicine is that …

Background Colorectal cancer (CRC) screening can effectively reduce disease-related
mortality by detecting CRC at earlier stages. We have previously demonstrated that the …

Red meat is associated with increased risk of colorectal cancer and increases the
endogenous formation of N-nitrosocompounds (NOC). To investigate the genotoxic effects of …

BACKGROUND & AIMS: Several noninvasive tests have been developed for colorectal
cancer (CRC) screening. We compared the sensitivities of a multimarker test for stool DNA …

Assay of molecular markers in stool represents a promising noninvasive approach to screen
colorectal cancer. Given that neoplasms exfoliate abundantly into the lumen and that DNA …

Colorectal cancer (CRC), although a significant cause of morbidity and mortality worldwide,
has seen a declining incidence and mortality in countries with programmatic screening …

Background Colorectal cancer (CRC) screening is the most efficient strategy to reduce
disease-related mortality. Frequent aberrant DNA methylation is known to occur in selected …

A variety of noninvasive molecular approaches to colorectal cancer screening are emerging
with potential to improve screening effectiveness and user-friendliness. These approaches …