Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Antimicrobial resistance is directly responsible for more deaths per year than either
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …

Efficient treatment of chronic lung infections caused by Pseudomonas aeruginosa biofilms is
a great challenge because of drug tolerance and immune evasion issues. Here, we develop …

Chronic infection with the bacterial pathogen Pseudomonas aeruginosa often leads to
coexistence of heterogeneous populations carrying diverse mutations. In particular, loss-of …

Protein trafficking across the bacterial envelope is a process that contributes to the
organisation and integrity of the cell. It is the foundation for establishing contact and …

Pseudomonas aeruginosa is one of the most dominant pathogens in cystic fibrosis (CF)
airway disease and contributes to significant inflammation, airway damage, and poorer …

Pseudomonas aeruginosa (P. aeruginosa) biofilms are associated with a wide range of
infections, from chronic tissue diseases to implanted medical devices. In a biofilm, the …

Innate immune adaptor proteins are critical components of the innate immune system that
propagate pro‐inflammatory responses from their upstream receptors, and lead to pathogen …

Pseudomonas aeruginosa (P. aeruginosa) can cause severe acute infections, including
pneumonia and sepsis, and cause chronic infections, commonly in patients with structural …

Pseudomonas aeruginosa relies on its complex cellular regulatory network to produce a
series of virulence factors and to cause various acute and chronic infections in a wide range …