A sex-and gender-informed perspective increases rigor, promotes discovery, and expands
the relevance of biomedical research. In the current era of accountability to present data for …

Background: Recent technological advances in epigenome profiling have led to an
increasing number of studies investigating the role of the epigenome in obesity. There is …

Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

Reduced levels of global DNA methylation are associated with genomic instability and are
independent predictors of cancer risk. Little is known about the environmental determinants …

The impact of cigarette smoking can persist for extended periods following smoking
cessation and may involve epigenetic reprogramming. Changes in DNA methylation …

Epigenetic processes are primary candidates when searching for mechanisms that can
stably modulate gene expression and metabolic pathways according to early life conditions …

Alterations in DNA methylation patterns, both at specific loci and overall in the genome, have
been associated with many different health outcomes. In cancer and other diseases, most of …

Environmentally induced epigenetic alterations are related to mental health. We investigated
quantitative DNA methylation status before and after an acute psychosocial stressor in two …

Background Disease risk and incidence between males and females reveal differences, and
sex is an important component of any investigation of the determinants of phenotypes or …

Lifestyle factors, such as diet, smoking, physical activity, and body weight management, are
known to constitute the majority of cancer causes. Epigenetics has been widely proposed as …