Natriuretic peptides are a family of structurally related but genetically distinct
hormones/paracrine factors that regulate blood volume, blood pressure, ventricular …

▪ Abstract Steroid hormone biosynthesis is acutely regulated by pituitary trophic hormones
and other steroidogenic stimuli. This regulation requires the synthesis of a protein whose …

Spät, András, and László Hunyady. Control of Aldosterone Secretion: A Model for
Convergence in Cellular Signaling Pathways. Physiol Rev 84: 489–539, 2004; …

In the 60 years that have passed since the discovery of the mineralocorticoid hormone
aldosterone, much has been learned about its synthesis (both adrenal and extra-adrenal) …

Expression of the genes that mediate the first steps in steroidogenesis, the steroidogenic
acute regulatory protein (STARD1), the cholesterol side-chain cleavage enzyme …

The mechanism by which cortisol is produced in adrenal Cushing's syndrome, when ACTH
is suppressed, was previously unknown and was referred to as being “autonomous.” More …

Aldosterone is a steroid hormone synthesized in and secreted from the outer layer of the
adrenal cortex, the zona glomerulosa. Aldosterone is responsible for regulating sodium …

Steroid hormones are synthesized in steroidogenic cells of the adrenal, ovary, testis,
placenta and brain and are essential for normal reproductive function and bodily …

The rate-limiting, committed, and regulatable step in steroid hormone biosynthesis is the
transport of cholesterol from the outer to the inner mitochondrial membrane, a process that is …

Steroidogenic acute regulatory protein (StAR) is a vital accessory protein required for
biosynthesis of steroid hormones from cholesterol. The present study shows that in primary …