Glioblastoma (GBM) is uniformly fatal with a median survival of just over 1 year, despite best
available treatment including radiotherapy (RT). Impacts of prior brain RT on recurrent …

Radiation therapy, the most commonly used for the treatment of brain tumors, has been
shown to be of major significance in tu-mor control and survival rate of brain tumor patients …

The main characteristic of glioma is recurrence, even after intensive multidisciplinary
treatment. Studies show that enhanced invasive ability will increase the ability of tumor cells …

This study is to investigate the molecular mechanism of radiation-enhanced cell
invasiveness of hepatocellular carcinoma (HCC) correlating with clinical patients …

Mast cells accumulate in tissues undergoing angiogenesis during tumor growth, wound
healing, and tissue repair. Mast cells can secrete angiogenic factors such as vascular …

Despite aggressive clinical treatment, recurrence of glioblastoma multiforme (GBM) is
unavoidable, and the clinical outcome is still poor. A convincing explanation is the …

Abstract Effects of ionising radiation on extracellular matrix (ECM)-modulated cell survival
and on adhesion and invasion are not well understood. In particular, the aggressiveness of …

Angiogenesis, the process by which new branches sprout from existing vessels, requires the
degradation of the vascular basement membrane and remodeling of the ECM in order to …

PURPOSE: Blood-brain barrier (BBB) disruption is one of the major consequences of
radiation-induced normal tissue injury in the central nervous system. We examined the …

Glioblastoma multiforme (GBM) is the most invasive brain tumor. We have previously
reported that the transcription factor PAX6 suppresses the tumorigenecity of GBM cells. By …