Systemic sclerosis (SSc) is a complex disease characterized by early microvascular
abnormalities, immune dysregulation and chronic inflammation, and subsequent fibrosis of …

Systemic sclerosis (SSc) is a multisystem autoimmune and vascular disease resulting in
fibrosis of various organs with unknown etiology. Accumulating evidence suggests that a …

Objective Systemic sclerosis (SSc) features multiorgan fibrosis orchestrated predominantly
by activated myofibroblasts. Endothelial-to-mesenchymal transition (EndoMT) is a …

Systemic sclerosis (SSc) is a multisystem connective tissue disorder featured by vascular
injury and fibrosis of the skin and various internal organs with autoimmune background …

Systemic sclerosis (SS c) is a multisystem autoimmune disease characterized by
vasculopathy and tissue fibrosis of the skin and various internal organs. A series of genetic …

Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of
genetic and environmental risk factors, is characterized by progressive fibrosis and …

Systemic sclerosis (SSc) is a complex rheumatologic autoimmune disease in which
inflammation, fibrosis, and vasculopathy share several pathogenic pathways that lead to …

Systemic sclerosis (SSc, scleroderma) is a complex multisystem disease characterized by
autoimmunity, vasculopathy, and most notably, fibrosis. Multiple lines of evidence …

Systemic sclerosis (SSc) is an autoimmune disease characterized by significant vascular
alterations and multi-organ fibrosis. Microvascular alterations are the first event of SSc and …

Systemic sclerosis (SSc), or scleroderma, is a multisystem autoimmune disorder
characterized by vasculopathy and fibrosis in the skin and internal organs, most frequently in …