New antimicrobial strategies based on metal complexes

M Claudel, JV Schwarte, KM Fromm - Chemistry, 2020 - mdpi.com
Traditional organic antimicrobials mainly act on specific biochemical processes such as
replication, transcription and translation. However, the emergence and wide spread of …

Azo-Schiff base derivatives of transition metal complexes as antimicrobial agents

M Pervaiz, S Sadiq, A Sadiq, U Younas, A Ashraf… - Coordination Chemistry …, 2021 - Elsevier
AMR (Antimicrobial-resistant) pathogens like MRSA (Methicillin-Resistant Staphylococcus
aureus) have become prodigious peril to human health in the past couple of years with the …

Synthesis, DFT, biological and molecular docking analysis of novel manganese (II), Iron (III), Cobalt (II), Nickel (II), and Copper (II) Chelate Complexes Ligated by 1-(4 …

YAA Alghuwainem, HMA El-Lateef, MM Khalaf… - International Journal of …, 2022 - mdpi.com
Novelmanganese (II), iron (III), cobalt (II), nickel (II), and copper (II) chelates were
synthesized and studied using elemental analysis (EA), infrared spectroscopy, mass …

Current development of 1, 2, 3-triazole derived potential antimalarial scaffolds: Structure activity relationship (SAR) and bioactive compounds

SMA Rahman, JS Bhatti, S Thareja, V Monga - European Journal of …, 2023 - Elsevier
Malaria is among one of the most devastating and deadliest parasitic disease in the world
claiming millions of lives every year around the globe. It is a mosquito-borne infectious …

Synthesis, characterization, DFT calculation, DNA binding and antimicrobial activities of metal complexes of dimedone arylhydrazone

KS Abou-Melha, GA Al-Hazmi, I Althagafi… - Journal of Molecular …, 2021 - Elsevier
The diazotization, coupling and metallization process was employed to create hydrazone
chelating ligand (HL) and its Co (II), Cu (II) and Ni (II) complexes. Elemental analysis, FT-IR …

Pincer complexes derived from tridentate Schiff bases for their use as antimicrobial metallopharmaceuticals

A Aragón-Muriel, V Reyes-Márquez… - Inorganics, 2022 - mdpi.com
Within the current challenges in medicinal chemistry, the development of new and better
therapeutic agents effective against infectious diseases produced by bacteria, fungi, viruses …

Design, facile synthesis, spectroscopic characterization, and medicinal probing of metal‐based new sulfonamide drugs: A theoretical and spectral study

AU Hassan, SH Sumrra, MA Raza… - Applied …, 2021 - Wiley Online Library
Sulfonamide core‐based new ligands 4‐{[(2, 4‐dihydroxyphenyl) methylidene] amino}
benzene‐1‐sulfonamide as (L1) and 4‐[(2, 4‐dihydroxyphenyl) methylidene] amino‐N‐(5 …

New Copper Complexes with Antibacterial and Cytotoxic Activity

AC Hangan, RL Lucaciu, A Turza, L Dican… - International Journal of …, 2023 - mdpi.com
The discovery of a new non-toxic metal complex with biological activity represents a very
active area of research. Two Cu+ 2 complexes,[Cu4 (L1) 4 (OH) 4 (DMF) 2 (H2O)](C1)(HL1 …

Experimental and DFT studies of a novel Schiff base sulfonamide derivative ligand and its palladium (II) and platinum (IV) complexes: antimicrobial activity, cytotoxicity …

A Bouzaheur, A Bouchoucha, KS Larbi… - Journal of Molecular …, 2022 - Elsevier
This present work reports the synthesis, characterization, and vibrational spectra (FTIR, 1 H
and 13 C NMR and UV-Visible absorption) of a newly synthesized heterocyclic Schiff base …

Bioactive Co(II), Ni(II), and Cu(II) Complexes Containing a Tridentate Sulfathiazole-Based (ONN) Schiff Base

A Reiss, N Cioateră, A Dobrițescu, M Rotaru… - Molecules, 2021 - mdpi.com
New Co (II), Ni (II), and Cu (II) complexes were synthesized with the Schiff base ligand
obtained by the condensation of sulfathiazole with salicylaldehyde. Their characterization …