Oral squamous cell carcinoma (OSCC) usually originates from the precancerous lesions of
oral mucosa and accounts for approximately 90% of oral cancers. Current therapeutic …

Simple Summary The extensive array of applications in 3D culture models closely mimics
the precise physiological conditions of in vivo settings, enabling the investigation of …

Abstract Background Tumor-associated macrophages (TAMs) have a leading position in the
tumor microenvironment. Previously, we have demonstrated that M1-like TAMs activated by …

Cancer‐derived small extracellular vesicles (sEVs) are emerging as crucial mediators of
intercellular communication between cancer cells and M2‐tumor‐associated macrophages …

Oral squamous cell carcinoma (OSCC) is a common head and neck cancer with a high
recurrence rate and a low 5-year survival rate. Tumor-associated macrophages (TAMs) are …

Simple Summary TNF-α is of interest in oral squamous cell carcinoma (OSCC), with its
demonstrated presence affecting both tumour and stromal inflammatory cells to enhance …

Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral and maxillofacial
malignancies, characterized by a low five-year survival rate primarily caused by invasion …

Oral cancer is one of the leading causes of cancer-related deaths, and it has become a
matter of serious concern due to the alarming rise in its incidence rate worldwide. Despite …

Introduction Oral Squamous Cell Carcinomas (OSCC) are mostly related to tobacco
consumption eventually associated to alcohol (Smoker/Drinker patients: SD), but 25-30% of …

Oral squamous cell carcinoma (OSCC) has a five-year survival rate of less than 50% due to
its susceptibility to invasion and metastasis. Crosstalk between tumor cells and …