Keratinocyte differentiation is an essential process for epidermal stratification and stratum
corneum formation. Keratinocytes proliferate in the basal layer of the epidermis and start …

MicroRNAs (miRNAs) are small non‐coding RNAs that have emerged as central regulators
of gene expression and powerful biomarkers of disease. Much is yet unknown about their …

Psoriasis is an auto-inflammatory skin disease characterized by abnormal activation of
epidermal keratinocytes, aberrant neovascularization, and dysregulation of immune cells …

Psoriasis is an inflammatory skin disease accompanied with chronic papulosquamous
lesions and multiple comorbidities that considerably affect patients' quality of life. In order to …

Background Psoriasis is an immune‐mediated inflammatory skin disease, in which an
interplay between infiltrating immune cells and keratinocytes sustains chronic skin …

Aims: In this study, we aimed to decipher the impact of enhancer of zeste homolog 2 (EZH2)
in psoriasis as well as the underlying mechanism. Methods: A mouse model of psoriasis was …

Psoriasis is a chronic autoimmune skin disease driven by dysregulations at the cellular,
genomic and genetic levels. MicroRNAs are key mediators of gene expression regulation …

In burn injuries, risk factors and limitations to treatment success are difficult to assess
clinically. However, local cellular responses are characterized by specific gene-expression …

The role of microRNAs (miRNAs) during keratinocyte (KC) differentiation and in skin
diseases with epidermal phenotypes has attracted strong interest over the past few years …

Background Psoriasis is a chronic inflammatory skin disease with disturbed interplay
between immune cells and keratinocytes. A strong IFN-γ signature is characteristic for …