Metastasis and MAPK pathways

M Kciuk, A Gielecińska, A Budzinska… - International journal of …, 2022 - mdpi.com
Cancer is a leading cause of death worldwide. In many cases, the treatment of the disease is
limited due to the metastasis of cells to distant locations of the body through the blood and …

Signaling, metabolism, and cancer: An important relationship for therapeutic intervention

M Vaghari‐Tabari, GA Ferns, D Qujeq… - Journal of cellular …, 2021 - Wiley Online Library
In cancerous cells, significant changes occur in the activity of signaling pathways affecting a
wide range of cellular activities ranging from growth and proliferation to apoptosis …

CircDNAJC11 interacts with TAF15 to promote breast cancer progression via enhancing MAPK6 expression and activating the MAPK signaling pathway

B Wang, H Chen, Y Deng, H Chen, L Xing… - Journal of Translational …, 2023 - Springer
Background Breast cancer (BC) is a common malignant tumor in women worldwide. Circular
RNA (circRNA) has been proven to play a critical role in BC progression. However, the exact …

Anti-tumor activity of resveratrol against gastric cancer: A review of recent advances with an emphasis on molecular pathways

M Ashrafizadeh, H Rafiei, R Mohammadinejad… - Cancer Cell …, 2021 - Springer
Gastric cancer (GC) is one of the most common cancers with high malignancy. In spite of the
great development in diagnostic tools and application of anti-tumor drugs, we have not …

Role of regulatory miRNAs of the PI3K/AKT signaling pathway in the pathogenesis of breast cancer

F Rahmani, GA Ferns, S Talebian, M Nourbakhsh… - Gene, 2020 - Elsevier
Breast cancer is one of the most common tumors in women. Current data indicate that the
overexpression of some microRNAs (miRNAs) is associated with breast cancer, in relation to …

Plasma oncology: Adjuvant therapy for head and neck cancer using cold atmospheric plasma

X Li, X Rui, D Li, Y Wang, F Tan - Frontiers in Oncology, 2022 - frontiersin.org
The worldwide incidence of head and neck cancer (HNC) exceeds half a million cases
annually, and up to half of the patients with HNC present with advanced disease. Surgical …

[HTML][HTML] TIMP-2 regulates 5-Fu resistance via the ERK/MAPK signaling pathway in colorectal cancer

G Zhang, X Luo, Z Wang, J Xu, W Zhang… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Fluorouracil (5-Fu) is the first-line chemotherapeutic option for colorectal cancer. However,
its efficacy is inhibited by drug resistance. Cytokines play an important role in tumor drug …

[HTML][HTML] The coexistence of aflatoxin M1 and ochratoxin A induced intestinal barrier disruption via the regulation of key differentially expressed microRNAs and long …

YN Gao, L Min, X Yang, JQ Wang, N Zheng - … and Environmental Safety, 2023 - Elsevier
Food safety can be seriously threatened by the existence of both aflatoxin M1 (AFM1) and
ochratoxin A (OTA) in milk and corresponding products. The importance of intestine integrity …

Unveiling the genetic and epigenetic landscape of colorectal cancer: new insights into pathogenic pathways

H Postwala, Y Shah, PS Parekh, MR Chorawala - Medical Oncology, 2023 - Springer
Colorectal cancer (CRC) is a complex disease characterized by genetic and epigenetic
alterations, playing a crucial role in its development and progression. This review aims to …

Role of regulatory miRNAs of the Wnt/β-catenin signaling pathway in tumorigenesis of breast cancer

F Rahmani, AT Tabrizi, P Hashemian, S Alijannejad… - Gene, 2020 - Elsevier
Breast cancer is the most commonly diagnosed malignancy in women worldwide. Recently,
uncontrolled expression of microRNAs was detected in several human disorders like …