Living sample viability measurement methods from traditional assays to nanomotion

H Al-Madani, H Du, J Yao, H Peng, C Yao, B Jiang… - Biosensors, 2022 - mdpi.com
Living sample viability measurement is an extremely common process in medical,
pharmaceutical, and biological fields, especially drug pharmacology and toxicology …

[HTML][HTML] Nanomotion detection-based rapid antibiotic susceptibility testing

S Kasas, A Malovichko, MI Villalba, ME Vela… - Antibiotics, 2021 - mdpi.com
Rapid antibiotic susceptibility testing (AST) could play a major role in fighting multidrug-
resistant bacteria. Recently, it was discovered that all living organisms oscillate in the range …

Probing nanomotion of single bacteria with graphene drums

IE Rosłoń, A Japaridze, PG Steeneken… - Nature …, 2022 - nature.com
Motion is a key characteristic of every form of life. Even at the microscale, it has been
reported that colonies of bacteria can generate nanomotion on mechanical cantilevers, but …

An Optical Fiber-Based Nanomotion Sensor for Rapid Antibiotic and Antifungal Susceptibility Tests

J Zhou, C Liao, M Zou, MI Villalba, C Xiong, C Zhao… - Nano Letters, 2024 - ACS Publications
The emergence of antibiotic and antifungal resistant microorganisms represents nowadays
a major public health issue that might push humanity into a post-antibiotic/antifungal era …

Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform

A Sturm, G Jóźwiak, MP Verge, L Munch… - Nature …, 2024 - nature.com
Antimicrobial resistance (AMR) is a major public health threat, reducing treatment options for
infected patients. AMR is promoted by a lack of access to rapid antibiotic susceptibility tests …

Differences in bacteria nanomotion profiles and neutrophil nanomotion during phagocytosis

SN Pleskova, EV Lazarenko, NA Bezrukov… - Frontiers in …, 2023 - frontiersin.org
The main goal of this work is to highlight the connection between nanomotion and the
metabolic activity of living cells. We therefore monitored the nanomotion of four different …

Fractal analysis and FEM assessment of soft tissue affected by fibrosis

AY Prieto-Vázquez, A Cuautle-Estrada… - Fractal and …, 2023 - mdpi.com
This research shows an image processing method to determine the liver tissue's mechanical
behavior under physiological damage caused by fibrosis pathology. The proposed method …

The Dynamics of Single-Cell Nanomotion Behaviour of Saccharomyces cerevisiae in a Microfluidic Chip for Rapid Antifungal Susceptibility Testing

V Radonicic, C Yvanoff, MI Villalba, S Kasas… - Fermentation, 2022 - mdpi.com
The fast emergence of multi-resistant pathogenic yeasts is caused by the extensive—and
sometimes unnecessary—use of broad-spectrum antimicrobial drugs. To rationalise the use …

Machine learning method for the classification of the state of living organisms' oscillations

D Kweku, MI Villalba, RG Willaert… - … in Bioengineering and …, 2024 - frontiersin.org
The World Health Organization highlights the urgent need to address the global threat
posed by antibiotic-resistant bacteria. Efficient and rapid detection of bacterial response to …

Correlating nanoscale motion and ATP production in healthy and favism erythrocytes: a real-time nanomotion sensor study

M Girasole, S Dinarelli, G Longo - Frontiers in Microbiology, 2023 - frontiersin.org
Introduction Red blood cells (RBCs) are among the simplest, yet physiologically relevant
biological specimens, due to their peculiarities, such as their lack of nucleus and simplified …