This paper focuses on depression that precedes an onset of manifest bipolar disorder as
early stage bipolar disorder. First, we review how to pragmatically identify the clinical …

Patients with depressive disorders are especially prone to suicide risk. Among the clinical
predictors of suicidality, those specifically related to depressive disorders have not been …

Background Mood disorders are known to be associated with poor socioeconomic
outcomes, but no study has examined these associations across the entire worklife course …

Importance Although the usefulness of polygenic risk scores as a measure of genetic liability
for major depression (MD) has been established, their association with depression in the …

Objective: The authors investigated the associations between polygenic liability and
progression to bipolar disorder or psychotic disorders among individuals diagnosed with …

Background Register‐based studies of major depressive disorder (MDD) do not capture all
prevalent cases, as untreated cases and diagnoses made by general practitioners are not …

Many patients with bipolar disorder (BD) are initially misdiagnosed with major depressive
disorder (MDD) and are treated with antidepressants, whose potential iatrogenic effects are …

Objective Examine the overall incidence of medically treated depression in Denmark among
individuals 15–44 years old, and estimate the 5‐year cumulative incidence of psychiatric …

Objective: The authors investigated associations between polygenic liabilities for bipolar
disorder, major depression, and schizophrenia and episode polarity among individuals with …

Background Previous studies have shown that bipolar disorder (BD) patients frequently
present with difficulties in interpersonal relationships, education or employment and suffer …