CRISPR in cancer biology and therapy

A Katti, BJ Diaz, CM Caragine, NE Sanjana… - Nature Reviews …, 2022 - nature.com
Over the past decade, CRISPR has become as much a verb as it is an acronym,
transforming biomedical research and providing entirely new approaches for dissecting all …

Identification of NOXA as a pivotal regulator of resistance to CAR T-cell therapy in B-cell malignancies

X Yan, D Chen, Y Wang, Y Guo, C Tong… - … and Targeted Therapy, 2022 - nature.com
Despite the remarkable success of chimeric antigen receptor (CAR) T-cell therapy for
treating hematologic malignancies, resistance and recurrence still occur, while the markers …

[HTML][HTML] Advancements in CRISPR screens for the development of cancer immunotherapy strategies

YR Li, Z Lyu, Y Tian, Y Fang, Y Zhu, Y Chen… - Molecular Therapy …, 2023 - cell.com
CRISPR screen technology enables systematic and scalable interrogation of gene function
by using the CRISPR-Cas9 system to perturb gene expression. In the field of cancer …

The Effects of CRISPR Cas 9 on Leukemia Treatment

S Majdi, Y Alilou - International Journal of BioLife Sciences (IJBLS), 2024 - jobiost.com
Background and Aim: Leukemia is a group of blood malignancies marked by uncontrolled
cell growth in bone marrow and blood, disrupting immune function. Treatment has …

[图书][B] Defining Natural Killer Cell Responses to HIV

NQ Zhao - 2020 - search.proquest.com
Human immunodeficiency virus (HIV) remains a major global public health issue, and in the
continued absence of a cure or vaccine, novel treatment and prevention strategies are …