A comprehensive review on invasomal carriers incorporating natural terpenes for augmented transdermal delivery
Background Transdermal drug delivery is one of the most widely used drug administration
routes, which offer several advantages over other routes of drug delivery. The apical layer of …
routes, which offer several advantages over other routes of drug delivery. The apical layer of …
Self-emulsifying drug delivery systems and their marketed products: a review
GV Betageri - Asian Journal of Pharmaceutics (AJP), 2019 - asiapharmaceutics.info
Self-emulsifying drug delivery systems (SEDDS) are one of the proven methods to increase
solubility and bioavailability of poorly soluble drugs. SEDDS are isotropic mixtures …
solubility and bioavailability of poorly soluble drugs. SEDDS are isotropic mixtures …
Self-nanoemulsifying drug delivery system (SNEDDS) with enhanced solubilization of nystatin for treatment of oral candidiasis: Design, optimization, in vitro and in …
The aim of the present study is to develop and optimize self-nanoemulsifying drug delivery
systems (SNEDDSs) to improve the per-oral bioavailability of poorly soluble polyene …
systems (SNEDDSs) to improve the per-oral bioavailability of poorly soluble polyene …
Nanoemulgel, an innovative carrier for diflunisal topical delivery with profound anti-inflammatory effect: In vitro and in vivo evaluation
Purpose Rheumatoid arthritis is an autoimmune disorder that directly affects joints. However,
other body organs including heart, eyes, skin, blood vessels and lungs may also be affected …
other body organs including heart, eyes, skin, blood vessels and lungs may also be affected …
Development of an optimized avanafil-loaded invasomal transdermal film: Ex vivo skin permeation and in vivo evaluation
OAA Ahmed, SM Badr-Eldin - International journal of pharmaceutics, 2019 - Elsevier
Avanafil (AVA) is a recent FDA approved selective phosphodiesterase type 5 inhibitor used
for oral treatment of erectile dysfunction. The oral bioavailability of the drug is challenged by …
for oral treatment of erectile dysfunction. The oral bioavailability of the drug is challenged by …
Preparation, optimization and evaluation of chitosan-based avanafil nanocomplex utilizing antioxidants for enhanced neuroprotective effect on PC12 cells
(1) Introduction: in recent decades, interdisciplinary research on the utilization of natural
products as “active moiety carriers” was focused on due to their superior safety profile …
products as “active moiety carriers” was focused on due to their superior safety profile …
Development of solid self-emulsifying formulation for improving the oral bioavailability of erlotinib
To improve the solubility and oral bioavailability of erlotinib, a poorly water-soluble
anticancer drug, solid self-emulsifying drug delivery system (SEDDS) was developed using …
anticancer drug, solid self-emulsifying drug delivery system (SEDDS) was developed using …
Solid lipid nanoparticles for transdermal delivery of avanafil: optimization, formulation, in-vitro and ex-vivo studies
Context: Avanafil (AVA) is used in the treatment of erectile dysfunction, but is reported for its
poor aqueous solubility. Solid lipid nanoparticles (SLNs) are lipid carriers that can greatly …
poor aqueous solubility. Solid lipid nanoparticles (SLNs) are lipid carriers that can greatly …
[HTML][HTML] Enhanced transdermal permeability of Terbinafine through novel nanoemulgel formulation; Development, in vitro and in vivo characterization
ME Elmataeeshy, MS Sokar, M Bahey-El-Din… - Future journal of …, 2018 - Elsevier
Terbinafine Hcl (TB) is a poorly water soluble antifungal drug. Topical nanoemulsion based
gel containing TB was prepared with a view to improve its solubility and antifungal activity. In …
gel containing TB was prepared with a view to improve its solubility and antifungal activity. In …
Intranasal administration of dolutegravir-loaded nanoemulsion-based in situ gel for enhanced bioavailability and direct brain targeting
Dolutegravir's therapeutic effectiveness in the management of neuroAIDS is mainly limited
by its failure to cross the blood–brain barrier. However, lipid-based nanovesicles such as …
by its failure to cross the blood–brain barrier. However, lipid-based nanovesicles such as …