Why primate models matter

KA Phillips, KL Bales, JP Capitanio… - American journal of …, 2014 - Wiley Online Library
Research involving nonhuman primates (NHPs) has played a vital role in many of the
medical and scientific advances of the past century. NHPs are used because of their …

[HTML][HTML] Focus: comparative medicine: Titi monkeys as a novel non-human primate model for the neurobiology of pair bonding

KL Bales, RA Del Razo, QA Conklin… - The Yale journal of …, 2017 - ncbi.nlm.nih.gov
It is now widely recognized that social bonds are critical to human health and well-being.
One of the most important social bonds is the attachment relationship between two adults …

The marmoset as a model of aging and age-related diseases

SD Tardif, KG Mansfield, R Ratnam, CN Ross… - ILAR …, 2011 - academic.oup.com
The common marmoset (Callithrix jacchus) is poised to become a standard nonhuman
primate aging model. With an average lifespan of 5 to 7 years and a maximum lifespan of …

Alternative models for small samples in psychological research: applying linear mixed effects models and generalized estimating equations to repeated measures …

C Muth, KL Bales, K Hinde… - Educational and …, 2016 - journals.sagepub.com
Unavoidable sample size issues beset psychological research that involves scarce
populations or costly laboratory procedures. When incorporating longitudinal designs these …

Neural correlates of pair-bonding in a monogamous primate

KL Bales, WA Mason, C Catana, SR Cherry… - Brain research, 2007 - Elsevier
The neurobiology of social bonding, despite its relevance to human mental health, has been
studied primarily in rodents. In this study we used position emission tomography (PET) …

[HTML][HTML] Long term effects of chronic intranasal oxytocin on adult pair bonding behavior and brain glucose uptake in titi monkeys (Plecturocebus cupreus)

R Arias-del Razo, MLV Vazquez, P Turcanu… - Hormones and …, 2022 - Elsevier
Intranasal oxytocin (IN OXT) administration has been proposed as a pharmacological
treatment for a range of biomedical conditions including neurodevelopmental disorders …

The marmoset monkey: a multi-purpose preclinical and translational model of human biology and disease

A Bert, DH Abbott, K Nakamura, E Fuchs - Drug discovery today, 2012 - Elsevier
The development of biologic molecules (monoclonal antibodies, cytokines, soluble
receptors) as specific therapeutics for human disease creates a need for animal models in …

Effects of Chronic and Acute Intranasal Oxytocin Treatments on Temporary Social Separation in Adult Titi Monkeys (Plecturocebus cupreus)

R Arias del Razo, ML Velasco Vazquez… - Frontiers in Behavioral …, 2022 - frontiersin.org
In socially monogamous titi monkeys, involuntary separation from a pair mate can produce
behavioral distress and increased cortisol production. The neuropeptide oxytocin (OXT) is …

Parenting costs time: Changes in pair bond maintenance across pregnancy and infant rearing in a monogamous primate (Plecturocebus cupreus)

CL Karaskiewicz, LR Witczak, AR Lau… - New directions for …, 2021 - Wiley Online Library
Relationships support social animals' health, but maintaining relationships is challenging.
When transitioning to parenthood, new parents balance pair‐bond maintenance with infant …

Spontaneous pathology of the common marmoset (Callithrix jacchus) and tamarins (Saguinus oedipus, Saguinus mystax)

JM David, EJ Dick Jr… - Journal of medical …, 2009 - Wiley Online Library
Background Marmosets and tamarins are increasingly used in research, but their pathology
remains poorly defined compared with Old World primates. Methods Necropsy records of …