Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for
millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host …

Intracellular pathogens have evolved various efficient molecular armaments to subvert
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …

Mycobacterium tuberculosis (Mtb), the causative agent of Tuberculosis (TB), remains a
pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where …

Autophagy is an ubiquitous homeostatic pathway in mammalian cells and plays a significant
role in host immunity. Substantial evidence indicates that the ability of Mycobacterium …

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis
(Mtb), and its incidence and mortality are increasing. The BCG vaccine was developed in the …

Mycobacterium tuberculosis (M. tb) utilizes the multifunctionality of its protein factors to
deceive the host. The unabated global incidence and prevalence of tuberculosis (TB) and …

Permeation through bacterial cells for exchange or uptake of biomolecules and ions
invariably depend upon the existence of pore-forming proteins (porins) in their outer …

Bacillus Calmette–Guérin (BCG) vaccination induces a type of immune memory known as"
trained immunity", characterized by the immunometabolic and epigenetic changes in innate …

Mycobacterial disease is an immense burden worldwide. This disease group includes
tuberculosis, leprosy (Hansen's disease), Buruli Ulcer, and non-tuberculous mycobacterial …

Autophagy is a fundamental cellular process that has important roles in innate and adaptive
immunity against a broad range of microbes. Many pathogenic microbes have evolved …