Type 1 diabetes (T1D) is a chronic autoimmune disease in which destruction or damaging of
the beta-cells in the islets of Langerhans results in insulin deficiency and hyperglycemia. We …

Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …

The rapidly increasing incidence of type 1 diabetes implies that environmental factors are
involved in the pathogenesis. Enteroviruses are among the suspected environmental …

Objective To identify the factors associated with diabetic ketoacidosis at diagnosis of type 1
diabetes in children and young adults. Design Systematic review. Data sources PubMed …

Inflammation is typically induced in response to a microbial infection. The release of
proinflammatory cytokines enhances the stimulatory capacity of antigen-presenting cells, as …

Type 1 diabetes results from a T cell-mediated destruction of insulin-producing pancreatic β
cells. Little is known on local factors contributing to migration of T cells to pancreatic tissue …

Enteric symptomology seen in early-stage severe acute respiratory syndrome (SARS)-2003
and COVID-19 is evidence of virus replication occurring in the intestine, liver and pancreas …

A primary insult to the pancreatic islets of Langerhans, leading to the activation of innate
immunity, has been suggested as an important step in the inflammatory process in type 1 …

Abstract Type 1 diabetes (T1D) is due to antigen-specific assaults on the insulin producing
pancreatic β-cells by diabetogenic T-helper (Th) 1 cells.(CXC motif) ligand (CXCL) 10, an …

The precise etiology of type 1 diabetes (T1D) is still unknown, but viruses have long been
suggested as a potential environmental trigger for the disease. However, despite decades of …