malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

[HTML][HTML] The molecular basis of antimalarial drug resistance in Plasmodium vivax

LE Buyon, B Elsworth, MT Duraisingh - International Journal for …, 2021 - Elsevier
Plasmodium vivax is the most geographically widespread cause of human malaria and is
responsible for the majority of cases outside of the African continent. While great progress …

Population genomics studies identify signatures of global dispersal and drug resistance in Plasmodium vivax

DN Hupalo, Z Luo, A Melnikov, PL Sutton, P Rogov… - Nature …, 2016 - nature.com
Plasmodium vivax is a major public health burden, responsible for the majority of malaria
infections outside Africa. We explored the impact of demographic history and selective …

[HTML][HTML] Multidisciplinary investigations of sustained malaria transmission in the Greater Mekong Subregion

L Cui, J Sattabongkot, PL Aung… - The American journal …, 2022 - ncbi.nlm.nih.gov
In the course of malaria elimination in the Greater Mekong Subregion (GMS), malaria
epidemiology has experienced drastic spatiotemporal changes with residual transmission …

Genomic variation in Plasmodium vivax malaria reveals regions under selective pressure

E Diez Benavente, Z Ward, W Chan, FR Mohareb… - PloS one, 2017 - journals.plos.org
Background Although Plasmodium vivax contributes to almost half of all malaria cases
outside Africa, it has been relatively neglected compared to the more deadly P. falciparum. It …

Contrasting Asymptomatic and Drug Resistance Gene Prevalence of Plasmodium falciparum in Ghana: Implications on Seasonal Malaria Chemoprevention

CC Dieng, L Gonzalez, K Pestana, SB Dhikrullahi… - Genes, 2019 - mdpi.com
Malaria is a significant public health problem in Ghana. Seasonal Malaria Chemoprevention
(SMC) using a combination of sulfadoxine-pyrimethamine and amodiaquine has been …

Drug resistance genes: pvcrt-o and pvmdr-1 polymorphism in patients from malaria endemic South Western Coastal Region of India

S Joy, B Mukhi, SK Ghosh, RN Achur, DC Gowda… - Malaria journal, 2018 - Springer
Background Malaria is highly prevalent in many parts of India and is mostly caused by the
parasite species Plasmodium vivax followed by Plasmodium falciparum. Chloroquine (CQ) …

malERA: An updated research agenda for insecticide and drug resistance in malaria elimination and eradication

malERA Refresh Consultative Panel on Insecticide … - PLoS …, 2017 - journals.plos.org
Resistance to first-line treatments for Plasmodium falciparum malaria and the insecticides
used for Anopheles vector control are threatening malaria elimination efforts. Suboptimal …

Evolution of the Plasmodium vivax multidrug resistance 1 gene in the Greater Mekong Subregion during malaria elimination

HG Ngassa Mbenda, M Wang, J Guo, FA Siddiqui… - Parasites & vectors, 2020 - Springer
Background The malaria elimination plan of the Greater Mekong Subregion (GMS) is
jeopardized by the increasing number of Plasmodium vivax infections and emergence of …

Exploration of Plasmodium vivax transmission dynamics and recurrent infections in the Peruvian Amazon using whole genome sequencing

AN Cowell, HO Valdivia, DK Bishop, EA Winzeler - Genome medicine, 2018 - Springer
Background Plasmodium vivax poses a significant challenge to malaria elimination due to
its ability to cause relapsed infections from reactivation of dormant liver parasites called …