Skeletal muscles are essential for vital functions such as movement, postural support,
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …

Skeletal muscle regeneration is a complex process orchestrated by multiple steps. Recent
findings indicate that inflammatory responses could play central roles in bridging initial …

Skeletal muscle requires a highly orchestrated coordination between multiple cell types and
their microenvironment to exert its function and to maintain its homeostasis and regenerative …

Satellite cells, the quintessential skeletal muscle stem cells, reside in a specialized local
environment whose anatomy changes dynamically during tissue regeneration. The plasticity …

Skeletal muscle regeneration is highly dependent on the inflammatory response. A wide
variety of innate and adaptive immune cells orchestrate the complex process of muscle …

Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

Sepsis is a major cause of morbidity and mortality in critically ill patients, and despite
advances in management, mortality remains high. In survivors, sepsis increases the risk for …

Macrophages are one of the first barriers of host defence against pathogens. Beyond their
role in innate immunity, macrophages play increasingly defined roles in orchestrating the …

Neuroinflammation is a recognized pathogenic mechanism underlying motor neuron
degeneration in amyotrophic lateral sclerosis (ALS), but the inflammatory mechanisms …

Objectives: As the catabolic state induced by septic shock together with the physical
inactivity of patients lead to the rapid loss of muscle mass and impaired function, the …