Water scarcity is rapidly spreading across the planet, threatening the population across the
five continents and calling for global sustainable solutions. Water reclamation is the most …

Coacervates are condensed liquid-like droplets, usually formed with oppositely charged
polymeric molecules. They have been studied extensively in colloid and interface science …

Inspired by the role of intracellular liquid-liquid phase separation (LLPS) in formation of
membraneless organelles, there is great interest in developing dynamic compartments …

The maturation of liquid-like protein condensates into amyloid fibrils has been associated
with several neurodegenerative diseases. However, the molecular mechanisms underlying …

Living cells harvest energy from their environments to drive the chemical processes that
enable life. We introduce a minimal system that operates at similar protein concentrations …

DEAD-box ATPases constitute a very large protein family present in all cells, often in great
abundance. From bacteria to humans, they play critical roles in many aspects of RNA …

Living cells have long been a source of inspiration for chemists. Their capacity of performing
complex tasks relies on the spatiotemporal coordination of matter and energy fluxes. Recent …

The mechanisms that underlie the regulation of enzymatic reactions by biomolecular
condensates and how they scale with compartment size remain poorly understood. Here we …

The cell cytosol is crowded with high concentrations of many different biomacromolecules,
which is difficult to mimic in bottom-up synthetic cell research and limits the functionality of …

Phase separation is thought to underlie spatial and temporal organization that is required for
controlling biochemical reactions in cells. Multivalence of interaction motifs, also known as …