Malaria, caused by protozoan parasites of the genus Plasmodium especially by the most
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …

Malaria is among the most devastating and widespread tropical parasitic diseases in which
most prevalent in developing countries. Antimalarial drug resistance is the ability of a …

Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …

Malaria remains a serious worldwide health danger and massive economic trouble to
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …

Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …

Atovaquone belongs to a naphthoquinone class of drugs and is used in combination with
proguanil (Malarone) for the treatment of acute, uncomplicated malaria caused by …

Malaria and cancer are chronic diseases. The challenge with drugs available for the
treatment of these diseases is drug toxicity and resistance. Ferrocene is a potent …

Introduction Pyrimidine nucleotides are essential for the parasite's growth and replication.
Parasites have only a de novo pathway for the biosynthesis of pyrimidine nucleotides …

Discovery and development of antimalarial drugs have long been dominated by single-
target therapy. Continuous effort has been made to explore and identify different targets in …

Plasmodium species, the causative agent of malaria, rely on glucose for energy supply
during blood stage. Inhibition of glucose uptake thus represents a potential strategy for the …