Cholangiocytes, the epithelial cells lining the intrahepatic and extrahepatic bile ducts, are
highly specialized cells residing in a complex anatomic niche where they participate in bile …

β-catenin (encoded by CTNNB1) is a subunit of the cell surface cadherin protein complex
that acts as an intracellular signal transducer in the WNT signaling pathway; alterations in its …

The liver is a central regulator of metabolism, and liver failure thus constitutes a major health
burden. Understanding how this complex organ develops during embryogenesis will yield …

How cells become specialized, or" mature," is important for cell and developmental biology.
While maturity is usually deemed a terminal fate, it may be more helpful to consider …

The liver is a highly regenerative organ, but its regenerative capacity is compromised in
severe liver diseases. Hepatocyte-driven liver regeneration that involves the proliferation of …

Due to the prominent role of the liver in the body and detoxification, its functionality can be
affected in an irreversible manner by diseases. This phenomenon renders the liver to stop …

Hexafluoropropylene oxide trimer acid (HFPO-TA), a novel alternative to perfluorooctanoic
acid (PFOA), has emerged as a potential environmental pollutant. Here, to investigate the …

В настоящем издании проанализированы и систематизированы сведения по
клиническому применению лекарственных средств, для которых гепатотропное …

Wnt/β-catenin signaling plays key roles not only during development but also in adult tissue
homeostasis. This is also evident in liver biology where many temporal roles of β-catenin …

Abstract Aflatoxin B 1 (AFB 1), a naturally occurring mycotoxin, is present in human placenta
and cord blood. AFB 1 at concentrations found in contaminated food commodities (0.25 and …