Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma

KMM Espíndola, RG Ferreira, LEM Narvaez… - Frontiers in …, 2019 - frontiersin.org
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in
foods such as coffee, wine, tea, and popular medicines such as propolis. This phenolic acid …

The potential of dandelion in the fight against gastrointestinal diseases: A review

Y Li, Y Chen, D Sun-Waterhouse - Journal of ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Dandelion (Taraxacum officinale Weber ex FH
Wigg.), as a garden weed grown globally, has long been consumed as a therapeutic herb …

Caffeic acid reduces A53T α-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse …

Y Zhang, Q Wu, L Zhang, Q Wang, Z Yang, J Liu… - Pharmacological …, 2019 - Elsevier
The human A53T mutant of α-synuclein tends to aggregate and leads to neurotoxicity in
familial Parkinson's disease (PD). The aggregation of α-synuclein is also found in sporadic …

Antiproliferative and apoptotic effects of caffeic acid on SK-Mel-28 human melanoma cancer cells

LP Pelinson, CE Assmann, TV Palma… - Molecular biology …, 2019 - Springer
Cutaneous melanoma (CM) is an extremely aggressive cancer presenting low survival and
high mortality. The vast majority of patients affected by this disease does not respond or …

Sugarcane straw polyphenols as potential food and nutraceutical ingredient

ALS Oliveira, MJ Carvalho, DL Oliveira, E Costa… - Foods, 2022 - mdpi.com
The sugarcane processing industry generates a large amount of straw, which has a negative
environmental impact, and high costs are associated with their elimination, wasting their …

[HTML][HTML] Ferulic acid attenuated difenoconazole-induced immunotoxicity in carp by inhibiting TRAF/TAK1/NF-κB, Nrf2 and p53 pathways

H Ma, Z Meng, L Zhou, H Feng, X Wu, Y Xin… - Ecotoxicology and …, 2023 - Elsevier
Difenoconazole (DFZ) is a classical triazole fungicide that causes immunosuppression in
non-target organisms. Ferulic acid (FA) is a polyphenolic molecule found in nature that has …

[HTML][HTML] Synergistic anticancer activity of combined use of caffeic acid with paclitaxel enhances apoptosis of non-small-cell lung cancer H1299 cells in vivo and in vitro

J Min, H Shen, W Xi, Q Wang, L Yin, Y Zhang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Caffeic acid (CA) is known to possess multiple biological activities
including anti-cancer activities. However, the molecular mechanisms underlying these …

Caffeic acid mitigates aflatoxin B1‐mediated toxicity in the male rat reproductive system by modulating inflammatory and apoptotic responses, testicular function, and …

SE Owumi, CE Irozuru, UO Arunsi… - Journal of food …, 2022 - Wiley Online Library
Abstract Aflatoxin B1 (AFB1) is a toxic metabolite of public health concern. The present study
investigates the protective effects of caffeic acid (CA) against AFB1‐induced oxidative stress …

Ferulic acid and hormesis: Biomedical and environmental implications

EJ Calabrese, E Agathokleous, V Calabrese - Mechanisms of ageing and …, 2021 - Elsevier
The present paper provides the first systematic assessment of the capacity of ferulic acid to
induce hormetic dose responses in biological systems. Ferulic acid induced hormetic effects …

Non-enzymatic antioxidants against Alzheimer's disease: prevention, diagnosis and therapy

A Varesi, LIM Campagnoli, A Carrara, I Pola, E Floris… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …