[HTML][HTML] Symphytum species: A comprehensive review on chemical composition, food applications and phytopharmacology

B Salehi, F Sharopov, T Boyunegmez Tumer… - Molecules, 2019 - mdpi.com
Symphytum species belongs to the Boraginaceae family and have been used for centuries
for bone breakages, sprains and rheumatism, liver problems, gastritis, ulcers, skin problems …

Symphytum genus—from traditional medicine to modern uses: an update on phytochemistry, pharmacological activity, and safety

A Trifan, E Wolfram, K Skalicka-Woźniak… - Phytochemistry …, 2024 - Springer
With around 34 recognized species, Symphytum genus (comfrey) has a noteworthy position
within the Boraginaceae family. Comfrey species have been empirically used since ancient …

Phytochemical Analysis of Symphytum officinale Root Culture Extract

V Le, V Dolganyuk, A Sukhikh, O Babich, S Ivanova… - Applied Sciences, 2021 - mdpi.com
Comfrey (Symphytum officinale) root preparations are known for their analgesic and anti-
inflammatory properties. In this study, the phenolic profile of extract samples of Symphytum …

LC-HRMS/MS phytochemical profiling of Symphytum officinale L. and Anchusa ochroleuca M. Bieb.(Boraginaceae): Unveiling their multi-biological potential via an …

A Trifan, G Zengin, KI Sinan, E Wolfram… - … of Pharmaceutical and …, 2021 - Elsevier
This study was aimed at providing a comprehensive phytochemical characterization and
multi-biological assessment of Symphytum officinale L., a medicinal plant with a noteworthy …

Globoidnan A, rabdosiin and globoidnan B as new phenolic markers in European‐sourced comfrey (Symphytum officinale L.) root samples

A Trifan, E Wolfram, N Esslinger… - Phytochemical …, 2021 - Wiley Online Library
Introduction Symphytum officinale L.(comfrey, Boraginaceae) is a cultivated or
spontaneously growing medicinal plant that is traditionally used for the treatment of bone …

[HTML][HTML] Anti-inflammatory properties of the genus Symphytum L.: a review

E Mahmoudzadeh, H Nazemiyeh… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
The Symphytum genus has been mainly used in traditional medicine, containing its anti-
inflammatory activity. Symphytum spp.'s active components, such as allantoin, polyphenols …

Preliminary investigation on chemical composition and bioactivity of differently obtained extracts from Symphytum aintabicum Hub.-Mor. &Wickens

G Zengin, KI Sinan, G Ak, S Angeloni, F Maggi… - Biochemical Systematics …, 2021 - Elsevier
Symphytum species, commonly known as comfrey, hold a long history of folk medicinal uses
for healing wounds, bone fractures and other pain resulting from inflammation. However …

Detoxification of comfrey (Symphytum officinale L.) extract using natural deep eutectic solvent (NADES) and evaluation of its anti-inflammatory, antioxidant, and …

AN Syarifah, H Suryadi, H Hayun… - Frontiers in …, 2023 - frontiersin.org
Comfrey (Symphytum officinale L.) contains rosmarinic acid which has different
pharmacological activities, such as antioxidant and anti-inflammatory activities. However …

Enrichment of rosmarinic acid from comfrey (Symphytum officinale L.) root extract by macroporous adsorption resins and molecular docking studies

P Alizadeh, P Alizadeh, M Rahimi, S Amjadi… - Industrial Crops and …, 2024 - Elsevier
The rosmarinic acid (RA) is known as the major phenolic compound in comfrey roots
possessing notable biological properties. This study aimed to enhance the polyphenol …

Novel approaches for the application of herbs for skin care

H Chopra, C Tsagkaris, L Matthews… - Current …, 2023 - ingentaconnect.com
Skin is the largest non–parenchymal organ of the human body. It constitutes a natural barrier
against pathogens and harmful environmental exposures and contributes to the human …