Sepsis is a significant public health concern, particularly affecting individuals above 70
years in developed countries. This is a crucial fact due to the increasing aging population …

A dysregulated host response to infection causes organ dysfunction in sepsis and septic
shock, two potentially fatal diseases. They continue to be major worldwide health burdens …

Mechanisms of mitochondrial dysfunction in sepsis are being extensively studied in recent
years. During our study, concentrations of microbial phenolic acids and mitochondrial …

Bloodstream infections (BSI) represent a serious bacterial infection with substantial
morbidity and mortality. Population-based studies demonstrate an increased incidence …

Background: Soluble urokinase plasminogen activator receptor (suPAR) is an inflammatory
biomarker that is used to predict mortality, readmission, early discharge, and LOS, thus …

Introduction In this study, we aimed to investigate the prognostic power of the first lactate
level measured in the emergency department (ED), National Early Warning Score (NEWS) …

Human microbiota produces metabolites that may enter the bloodstream and exert systemic
influence on various functions including mitochondrial. Mitochondria are not only a target for …

Objective: To evaluate the influence of patient characteristics on hyperlactatemia in an
infected population admitted to intensive care units and the influence of hyperlactatemia …

Introduction Using biomarkers to predict mortality in patients with sepsis is important
because these patients frequently have high mortality rates and unsatisfactory outcomes …

The aim of this study was to evaluate the role of miR-181a-5p in sepsis, and to further
explore the molecular mechanism. RAW 264.7 cells were stimulated with 1 μg/ml LPS for 4 …