Effects of intermittent fasting on health, aging, and disease

R De Cabo, MP Mattson - New England Journal of Medicine, 2019 - Mass Medical Soc
Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a
6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to …

The ups and downs of caloric restriction and fasting: from molecular effects to clinical application

SJ Hofer, D Carmona‐Gutierrez, MI Mueller… - EMBO Molecular …, 2022 - embopress.org
Age‐associated diseases are rising to pandemic proportions, exposing the need for efficient
and low‐cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and …

Dietary strategies for metabolic syndrome: a comprehensive review

S Castro-Barquero, AM Ruiz-León, M Sierra-Pérez… - Nutrients, 2020 - mdpi.com
Metabolic syndrome is a cluster of metabolic risk factors, characterized by abdominal
obesity, dyslipidemia, low levels of high-density lipoprotein cholesterol (HDL-c) …

Caloric restriction improves health and survival of rhesus monkeys

JA Mattison, RJ Colman, TM Beasley, DB Allison… - Nature …, 2017 - nature.com
Caloric restriction (CR) without malnutrition extends lifespan and delays the onset of age-
related disorders in most species but its impact in nonhuman primates has been …

New advances in metabolic syndrome, from prevention to treatment: the role of diet and food

D Ambroselli, F Masciulli, E Romano, G Catanzaro… - Nutrients, 2023 - mdpi.com
The definition of metabolic syndrome (MetS) has undergone several changes over the years
due to the difficulty in establishing universal criteria for it. Underlying the disorders related to …

Calorie restriction in humans: an update

J Most, V Tosti, LM Redman, L Fontana - Ageing research reviews, 2017 - Elsevier
Calorie restriction (CR), a nutritional intervention of reduced energy intake but with adequate
nutrition, has been shown to extend healthspan and lifespan in rodent and primate models …

Intermittent fasting interventions for treatment of overweight and obesity in adults: a systematic review and meta-analysis

L Harris, S Hamilton, LB Azevedo, J Olajide… - JBI Evidence …, 2018 - journals.lww.com
Objective: To examine the effectiveness of intermittent energy restriction in the treatment for
overweight and obesity in adults, when compared to usual care treatment or no treatment …

The effects of time restricted feeding on overweight, older adults: a pilot study

SD Anton, SA Lee, WT Donahoo, C McLaren, T Manini… - Nutrients, 2019 - mdpi.com
A growing body of evidence indicates that time restricted feeding (TRF), a popular form of
intermittent fasting, can activate similar biological pathways as caloric restriction, the only …

Mitohormesis: promoting health and lifespan by increased levels of reactive oxygen species (ROS)

M Ristow, K Schmeisser - Dose-response, 2014 - journals.sagepub.com
Increasing evidence indicates that reactive oxygen species (ROS), consisting of superoxide,
hydrogen peroxide, and multiple others, do not only cause oxidative stress, but rather may …

[HTML][HTML] Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans

S Timmers, E Konings, L Bilet, RH Houtkooper… - Cell metabolism, 2011 - cell.com
Resveratrol is a natural compound that affects energy metabolism and mitochondrial
function and serves as a calorie restriction mimetic, at least in animal models of obesity …