HLA-G is a molecule that was first known to confer protection to the fetus from destruction by
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …

Representing the major cause of morbidity and mortality for chronic lymphocytic leukemia
(CLL) patients, immunosuppression is a common feature of the disease. Effectors of the …

The HLA-G gene displays several peculiarities that are distinct from those of classical HLA
class I genes. The unique structure of the HLA-G molecule permits a restricted peptide …

The non-classical human leukocyte antigen (HLA) class Ib genes, HLA-E,-G and-F, are
located on chromosome 6 in the human major histocompatibility complex (MHC). HLA class …

Human leukocyte antigen G (HLA-G) is a non-classical major histocompatibility complex
(MHC) class I molecule that, through interaction with its receptors, exerts important …

HLA-G has a relevant role in immune response regulation. The overall structure of the HLA-
G coding region has been maintained during the evolution process, in which most of its …

HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows
lower frequency of polymorphism at the coding region but higher variability at regulatory …

Abstract Purpose of Review During the last decades, the field of regenerative medicine has
been rapidly evolving. Major progress has been made in the development of biological …

Human leukocyte antigen G (HLA-G) belongs to the family of non-classical HLA class I
genes, located within the major histocompatibility complex (MHC). HLA-G has been the …

Soluble human leukocyte antigen‐G (sHLA‐G) functions as a multiple immunoregulator. A
14 bp insertion (+ 14 bp)/deletion (− 14 bp) polymorphism in exon 8 of the HLA‐G gene has …