Paradigms of dynamic control of thyroid hormone signaling
AC Bianco, A Dumitrescu, B Gereben… - Endocrine …, 2019 - academic.oup.com
Thyroid hormone (TH) molecules enter cells via membrane transporters and, depending on
the cell type, can be activated (ie, T4 to T3 conversion) or inactivated (ie, T3 to 3, 3′-diiodo-l …
the cell type, can be activated (ie, T4 to T3 conversion) or inactivated (ie, T3 to 3, 3′-diiodo-l …
The classic pathways of thyroid hormone metabolism
AH van der Spek, E Fliers, A Boelen - Molecular and cellular endocrinology, 2017 - Elsevier
Thyroid hormones (TH) are crucial for growth and development and play an important role in
energy homeostasis. Although serum TH levels are relatively constant in the physiological …
energy homeostasis. Although serum TH levels are relatively constant in the physiological …
Thyroid hormone in the regulation of hepatocellular carcinoma and its microenvironment
P Manka, JD Coombes, R Boosman, K Gauthier… - Cancer letters, 2018 - Elsevier
Hepatocellular carcinoma (HCC) commonly arises from a liver damaged by extensive
inflammation and fibrosis. Various factors including cytokines, morphogens, and growth …
inflammation and fibrosis. Various factors including cytokines, morphogens, and growth …
Oxidative remote induction of type 3 deiodinase impacts nonthyroidal illness syndrome
TE Lehnen, R Marschner, F Dias… - Journal of …, 2020 - joe.bioscientifica.com
Imbalances in redox status modulate type 3 deiodinase induction in nonthyroidal illness
syndrome. However, the underlying mechanisms that lead to D3 dysfunction under redox …
syndrome. However, the underlying mechanisms that lead to D3 dysfunction under redox …
[HTML][HTML] Albumin is a secret factor involved in multidirectional interactions among the serotoninergic, immune and endocrine systems that supervises the mechanism of …
M Daujat-Chavanieu, M Kot - Pharmacology & Therapeutics, 2020 - Elsevier
This review focuses on albumin, which is involved in multidirectional interactions among the
immune, endocrine and serotoninergic systems and supervises the regulation of cytochrome …
immune, endocrine and serotoninergic systems and supervises the regulation of cytochrome …
Myocardial induction of type 3 deiodinase in dilated cardiomyopathy
AJ Wassner, RH Jugo, DM Dorfman, RF Padera… - Thyroid, 2017 - liebertpub.com
Background: The thyroid hormone–inactivating enzyme type 3 deiodinase (D3) is induced
during hypertrophic and ischemic cardiomyopathy, leading to a state of local cardiac …
during hypertrophic and ischemic cardiomyopathy, leading to a state of local cardiac …
ERK1/2 and JNK signaling synergistically modulate mitogenic effect of fibroblast growth factor 2 on liver cell
S Wu, W Zhang, S Ma, B Li, C Xu… - Cell Biology …, 2018 - Wiley Online Library
Proliferation of the adult hepatocyte population represents a central feature of tissue
regeneration after liver injury and resection. This process could be driven by a diverse range …
regeneration after liver injury and resection. This process could be driven by a diverse range …
[PDF][PDF] Role of thyroid hormones in pancreatic acinar cell regeneration following acute pancreatitis
E Malagola - 2018 - zora.uzh.ch
Acute pancreatitis is a debilitating inflammation of the pancreas, which leads to exocrine
dysfunction; in its severe form, the disease is associated with substantial morbidity and …
dysfunction; in its severe form, the disease is associated with substantial morbidity and …