Epithelial salt and water secretion serves a variety of functions in different organ systems,
such as the airways, intestines, pancreas, and salivary glands. In cystic fibrosis (CF), the …

In close interaction with photoreceptors, the retinal pigment epithelium (RPE) plays an
essential role for visual function. The analysis of RPE functions, specifically ion channel …

Epithelial cells of the gastrointestinal tract are an important barrier between the “milieu
interne” and the luminal content of the gut. They perform transport of nutrients, salts, and …

The SK/IK family of small and intermediate conductance calcium-activated potassium
channels contains four members, SK1, SK2, SK3 and IK1, and is important for the regulation …

Voltage-gated K+ channels belonging to Kv1–9 subfamilies are widely expressed in
excitable cells where they play an essential role in membrane hyperpolarization during an …

Homeostatic control of plasma K+ is a necessary physiological function. The daily dietary K+
intake of~ 100 mmol is excreted predominantly by the distal tubules of the kidney. About …

K+ secretion in the kidney and distal colon is a main determinant of K+ homeostasis. This
study investigated the identity of the relevant luminal secretory K+ ion channel in distal …

The intermediate (IKCa) and small (SKCa) conductance Ca2+-sensitive K+ channels in
endothelial cells (ECs) modulate vascular diameter through regulation of EC membrane …

Bone marrow mesenchymal stem cells (MSCs) are a promising cell source for regenerative
medicine; however, their cellular physiology is not fully understood. The present study aimed …

Zn, an essential micronutrient and second most abundant trace element in cell and tissues,
reduces stool output when administered to children with acute diarrhea. The mechanism by …