Indoloquinolines as scaffolds for drug discovery
J Lavrado, R Moreira, A Paulo - Current medicinal chemistry, 2010 - ingentaconnect.com
Traditional medicines have contributed greatly over the centuries to the discovery and
development of new therapeutic agents and indoloquinoline alkaloids may represent a new …
development of new therapeutic agents and indoloquinoline alkaloids may represent a new …
Advancements in the synthesis of fused tetracyclic quinoline derivatives
RA Mekheimer, MA Al-Sheikh, HY Medrasi… - RSC advances, 2020 - pubs.rsc.org
Fused tetracyclic systems containing a quinoline nucleus represent an important class of
heterocyclic bioactive natural products and pharmaceuticals because of their significant and …
heterocyclic bioactive natural products and pharmaceuticals because of their significant and …
6π-Electrocyclization in water: microwave-assisted synthesis of polyheterocyclic-fused quinoline-2-thiones
XY Li, Y Liu, XL Chen, XY Lu, XX Liang, SS Zhu… - Green …, 2020 - pubs.rsc.org
Microwave-assisted synthesis of polyheterocyclic-fused quinoline-2-thiones through the
annulation of ortho-heteroaryl anilines and CS2 was realized in water without using any …
annulation of ortho-heteroaryl anilines and CS2 was realized in water without using any …
Thionations Using a P4S10−Pyridine Complex in Solvents Such as Acetonitrile and Dimethyl Sulfone
J Bergman, B Pettersson, V Hasimbegovic… - The Journal of …, 2011 - ACS Publications
Tetraphosphorus decasulfide (P4S10) in pyridine has been used as a thionating agent for a
long period of time. The moisture-sensitive reagent has now been isolated in crystalline …
long period of time. The moisture-sensitive reagent has now been isolated in crystalline …
The aza-wittic reaction in heterocyclic synthesis. a review
S Eguchi, Y Matsushita, K Yamashita - Organic preparations and …, 1992 - Taylor & Francis
Phosphazo compounds containing a nitrogen-phosphorus double bond (phospha-h5-
azenes) are called iminophosphoranes and were tirst prepared via the reaction of tehary …
azenes) are called iminophosphoranes and were tirst prepared via the reaction of tehary …
Palladium(II)‐Catalyzed Cycloamidination via C(sp2)H Activation and Isocyanide Insertion
Y Wang, Q Zhu - Advanced Synthesis & Catalysis, 2012 - Wiley Online Library
An efficient method for the synthesis of nitrogen heterocycles containing a cyclic amidine
moiety has been developed. The process involves palladium‐catalyzed C (sp2) H …
moiety has been developed. The process involves palladium‐catalyzed C (sp2) H …
Iminophosphoranes: Versatile tools in heterocyclic synthesis
H Wamhoff, G Richardt, S Stölben - Advances in Heterocyclic Chemistry, 1995 - Elsevier
Within the last decades, the aza-Wittig reaction has assumed increasing importance for the
specific construction of many heterocyclic systems. This first comprehensive review provides …
specific construction of many heterocyclic systems. This first comprehensive review provides …
Studies of the reactions between indole-2, 3-diones (isatins) and 2-aminobenzylamine
J Bergman, R Engqvist, C Stålhandske, H Wallberg - Tetrahedron, 2003 - Elsevier
Reflux of equimolecular amounts 2-aminobenzylamine and isatins in acetic acid produced
indolo [3, 2-c] quinolin-6-ones in good yields. A proposed mechanism involving initial …
indolo [3, 2-c] quinolin-6-ones in good yields. A proposed mechanism involving initial …
Heck-like coupling and Pictet–Spengler reaction for the synthesis of benzothieno [3, 2-c] quinolines
E David, S Pellet-Rostaing, M Lemaire - Tetrahedron, 2007 - Elsevier
A series of 6-arylbenzothieno [3, 2-c] quinolines were synthesised in three steps from benzo
[b] thiophene. After a selective Heck-type coupling of benzo [b] thiophene with different o …
[b] thiophene. After a selective Heck-type coupling of benzo [b] thiophene with different o …
Heteroatom directed photoannulation: synthesis of indoloquinoline alkaloids: cryptolepine, cryptotackieine, cryptosanguinolentine, and their methyl derivatives
T Dhanabal, R Sangeetha, PS Mohan - Tetrahedron, 2006 - Elsevier
A three-step synthesis of indoloquinoline alkaloids is described. The reaction of 2, 3 and 4-
substituted haloquinolines with anilines afforded the respective anilinoquinolines, which …
substituted haloquinolines with anilines afforded the respective anilinoquinolines, which …