Ferroptosis-driven nanotherapeutics for cancer treatment
X Shan, S Li, B Sun, Q Chen, J Sun, Z He… - Journal of Controlled …, 2020 - Elsevier
The clinical efficacy of existing cancer therapies is still far from satisfactory. There is an
urgent need to integrate the emerging biomedical discovery and technological innovation …
urgent need to integrate the emerging biomedical discovery and technological innovation …
Remodeling the tumor microenvironment with emerging nanotherapeutics
Q Chen, G Liu, S Liu, H Su, Y Wang, J Li… - Trends in pharmacological …, 2018 - cell.com
The tumor microenvironment (TME) has profound impacts on cancer progression and
remodeling of the TME has emerged as a strategy to facilitate cancer therapy. Recently …
remodeling of the TME has emerged as a strategy to facilitate cancer therapy. Recently …
Emerging nanomedicines of paclitaxel for cancer treatment
Q Chen, S Xu, S Liu, Y Wang, G Liu - Journal of Controlled Release, 2022 - Elsevier
Malignant tumor is still a leading threat to human health. Despite the rapid development of
targeted therapeutic strategies, any treatment specifically acting on single target would …
targeted therapeutic strategies, any treatment specifically acting on single target would …
Nanoformulations for combination or cascade anticancer therapy
Nanoparticle drug formulations have been extensively investigated, developed, and in some
cases, approved by the Food and Drug Administration (FDA). Synergistic combinations of …
cases, approved by the Food and Drug Administration (FDA). Synergistic combinations of …
Nanoparticles for immune cytokine TRAIL-based cancer therapy
PPG Guimarães, S Gaglione, T Sewastianik… - ACS …, 2018 - ACS Publications
The immune cytokine tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has
received significant attention as a cancer therapeutic due to its ability to selectively trigger …
received significant attention as a cancer therapeutic due to its ability to selectively trigger …
Multiple hyperthermia-mediated release of TRAIL/SPION nanocomplex from thermosensitive polymeric hydrogels for combination cancer therapy
ZQ Zhang, SC Song - Biomaterials, 2017 - Elsevier
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) possesses strong anti-
cancer potential because of its ability to specifically kill cancer cells. However, clinical use of …
cancer potential because of its ability to specifically kill cancer cells. However, clinical use of …
Photodynamic PEG-coated ROS-sensitive prodrug nanoassemblies for core-shell synergistic chemo-photodynamic therapy
The combination of chemotherapy with photodynamic therapy (PDT) holds promising
applications in cancer therapy. However, co-encapsulation of chemotherapeutic agents and …
applications in cancer therapy. However, co-encapsulation of chemotherapeutic agents and …
Recent progress on nanomedicine-induced ferroptosis for cancer therapy
The current treatment strategies for cancer therapy have posed many problems in achieving
high efficacy. Therefore, an urgent step is needed to develop innovative therapies that can …
high efficacy. Therefore, an urgent step is needed to develop innovative therapies that can …
Nanotherapeutics for antimetastatic treatment
F Yang, Z Zhao, B Sun, Q Chen, J Sun, Z He, C Luo - Trends in Cancer, 2020 - cell.com
Tumor metastases, that is, the development of secondary tumors in organs distant from the
primary tumor, and their treatment remain a serious problem in cancer therapy. The unique …
primary tumor, and their treatment remain a serious problem in cancer therapy. The unique …
TRAIL therapy and prospective developments for cancer treatment
Abstract Tumor Necrosis Factor (TNF) Related Apoptosis-Inducing Ligand (TRAIL), an
immune cytokine of TNF-family, has received much attention in late 1990s as a potential …
immune cytokine of TNF-family, has received much attention in late 1990s as a potential …