Abstract IL-17 (IL-17A) has emerged as a key mediator of protection against extracellular
microbes, but this cytokine also drives pathology in various autoimmune diseases …

Our understanding of immunity to fungal pathogens has advanced considerably in recent
years. Particularly significant have been the parallel discoveries in the C-type lectin receptor …

Fungal infections are becoming increasingly prevalent in the human population and
contribute to morbidity and mortality in healthy and immunocompromised individuals …

Historically, the nature and extent of host damage by a microbe were considered highly
dependent on virulence attributes of the microbe. However, it has become clear that disease …

Interleukin-4 mediates important proinflammatory functions in asthma, including induction of
the IgE isotype switch, expression of VCAM-1 on endothelium, mucin production, 15 …

To define the role of interleukin (IL) 6 in Candida albicans infection, IL-6 deficient mice were
assessed for susceptibility to systemic or gastrointestinal infection, as well as for parameters …

Oropharyngeal and esophageal candidiases remain significant causes of morbidity in
human immunodeficiency virus (HIV)-infected patients, despite the dramatic ability of …

Oropharyngeal and vaginal candidiases are the most common forms of mucosal fungal
infections and are primarily caused by Candida albicans, a dimorphic fungal commensal …

Candida albicans causes mucosal and disseminated candidiasis, which represent serious
problems for the rapidly expanding immunocompromised population. Until recently, Th1 …

Protective immunity to the fungus Candida albicans is mediated by Ag-specific Th1 cells.
Paradoxically, some Th2 cytokines are required for the maintenance of Th1-mediated …