The significance of Cathepsin B in mediating radiation resistance in colon carcinoma cell line (Caco-2)
RF Abdelaziz, AM Hussein, MH Kotob, C Weiss… - International Journal of …, 2023 - mdpi.com
Cathepsins (Caths) are lysosomal proteases that participate in various physiological and
pathological processes. Accumulating evidence suggests that caths play a multifaceted role …
pathological processes. Accumulating evidence suggests that caths play a multifaceted role …
Development of New Leishmanicidal Compounds via Bioconjugation of Antimicrobial Peptides and Antileishmanial Guanidines
NCS Costa, LR Dos Anjos, JVM de Souza… - ACS …, 2023 - ACS Publications
Leishmaniasis refers to a collection of diseases caused by protozoa from the Leishmania
genus. These diseases, along with other parasitic afflictions, pose a significant public health …
genus. These diseases, along with other parasitic afflictions, pose a significant public health …
Enhancement of Radiation Sensitivity by Cathepsin L Suppression in Colon Carcinoma Cells
RF Abdelaziz, AM Hussein, MH Kotob, C Weiss… - International Journal of …, 2023 - mdpi.com
Cancer is one of the main causes of death globally. Radiotherapy/Radiation therapy (RT) is
one of the most common and effective cancer treatments. RT utilizes high-energy radiation …
one of the most common and effective cancer treatments. RT utilizes high-energy radiation …
Evidence of Guanidines Potential against Leishmania (Viannia) braziliensis: Exploring In Vitro Effectiveness, Toxicities and of Innate Immunity Response Effects
LR Dos Anjos, VMR de Souza, YAA Machado… - Biomolecules, 2023 - mdpi.com
Leishmaniasis is a complex group of infectious and parasitic diseases that afflict many
thousands of individuals across five continents. Leishmaniasis treatment remains a …
thousands of individuals across five continents. Leishmaniasis treatment remains a …
NMR and X-ray diffraction conformational study of guanidines
EH Zampieri, LR dos Anjos… - Journal of Molecular …, 2024 - Elsevier
Leishmaniasis is a neglected disease that affects regions such as South Asia, South Africa,
and Latin America, less developed regions. The research proposed the conformational …
and Latin America, less developed regions. The research proposed the conformational …
Exploratory Study of Guanidine Derivatives as Novel Anti Trypanosoma cruzi Scaffolds
Chagas disease (CD) is a neglected tropical parasitic disease caused by the protozoan
Trypanosoma cruzi. Unfortunately, the current etiological treatment for CD is unsatisfactory …
Trypanosoma cruzi. Unfortunately, the current etiological treatment for CD is unsatisfactory …
Design, Synthesis, and In Vitro and In Silico Evaluation of 1, 3, 4‐Oxadiazoles as Anti‐Trypanosoma cruzi and Anti‐Leishmania mexicana Agents
T Delgado-Maldonado, A Moreno-Rodriguez… - ChemMedChem - Wiley Online Library
A series of novel 4‐acetyl‐1, 3, 4‐oxadiazole derivatives was designed and synthesized for
their biological evaluation in vitro against Trypanosoma cruzi and Leishmania mexicana …
their biological evaluation in vitro against Trypanosoma cruzi and Leishmania mexicana …
Study of the Conformation of Bromated Guanidines with Potential Anti-Leishmania Activity
EH Zampieri, LR Dos Anjos, PH de Oliveira Santiago… - 2023 - preprints.org
Leishmaniasis are neglected diseases that affect regions such as South Asia, South Africa
and Latin America, less developed regions. Current treatment, for cutaneous …
and Latin America, less developed regions. Current treatment, for cutaneous …
Síntese e caracterização de compostos guanidínicos para estudos como leishmanicidas frente a L. amazonensis e L. infantum. Estudo da atividade inibitória da …
VP Moreira - 2023 - repositorio.unesp.br
A leishmaniose, uma doença negligenciada globalmente, é ocasionada por parasitas
protozoários pertencentes ao gênero Leishmania. Esta doença impacta milhões de pessoas …
protozoários pertencentes ao gênero Leishmania. Esta doença impacta milhões de pessoas …