Triazole derivatives as inhibitors of Alzheimer's disease: current developments and structure-activity relationships
M Xu, Y Peng, L Zhu, S Wang, J Ji… - European journal of …, 2019 - Elsevier
Alzheimer's disease (AD) is a well known neurodegenerative disorder alarming millions of
people worldwide and the subsequent epidemiological statistics highlights the implication of …
people worldwide and the subsequent epidemiological statistics highlights the implication of …
Applications of Fourier transform infrared spectroscopy to pharmaceutical preparations
Y Song, Y Cong, B Wang, N Zhang - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction: Various pharmaceutical preparations are widely used for clinical treatment.
Elucidation of the mechanisms of drug release and evaluation of drug efficacy in biological …
Elucidation of the mechanisms of drug release and evaluation of drug efficacy in biological …
Synthesis, biological activity and POM/DFT/docking analyses of annulated pyrano [2, 3-d] pyrimidine derivatives: Identification of antibacterial and antitumor …
Abstract New annulated pyrano [2, 3-d] pyrimidine derivatives were synthesized with
hydroxyl, methoxy, bromine, nitrile and nitro substituents on its skeleton. The correlated …
hydroxyl, methoxy, bromine, nitrile and nitro substituents on its skeleton. The correlated …
In vitro potential antiviral SARS-CoV-19-activity of natural product thymohydroquinone and dithymoquinone from Nigella sativa
Inflammation, oxidation, and compromised immunity all increase the dangers of COVID-19,
whereas many pharmaceutical protocols may lead to increased immunity such as ingesting …
whereas many pharmaceutical protocols may lead to increased immunity such as ingesting …
Synthesis of 5-methyl-2, 4-dihydro-3H-1, 2, 4-triazole-3-one's aryl Schiff base derivatives and investigation of carbonic anhydrase and cholinesterase (AChE, BuChE) …
Abstract Carbonic anhydrase enzymes (EC 4.2. 1.1, CAs) are metalloenzyme families that
catalyze the rapid conversion of H 2 O and CO 2 to HCO 3–and H+. CAs are found in …
catalyze the rapid conversion of H 2 O and CO 2 to HCO 3–and H+. CAs are found in …
The first peptide derivatives of dioxybiphenyl-bridged spiro cyclotriphosphazenes: In vitro cytotoxicity activities and DNA damage studies
In this study, we aimed to synthesize new peptide-substituted cyclotriphosphazenes from a
series of tyrosine-based peptides and dioxyphenyl-substituted spirocyclotriphosphazenes …
series of tyrosine-based peptides and dioxyphenyl-substituted spirocyclotriphosphazenes …
Green synthesis, antibacterial and antifungal evaluation of new thiazolidine-2, 4-dione derivatives: molecular dynamic simulation, POM study and identification of …
S Ahmed, AR Bhat, AK Rahiman… - Journal of …, 2023 - Taylor & Francis
In this study, a series of thiazolidine-2, 4-dione derivatives 3a–i were synthesized and
evaluated for antibacterial activity against Gram-positive and Gram-negative strains of …
evaluated for antibacterial activity against Gram-positive and Gram-negative strains of …
Benzoxazole-appended piperidine derivatives as novel anticancer candidates against breast cancer
Novel series of benzoxazole-appended piperidine derivatives were planned, synthesized
and screened against two breast cancer cell lines. Considerable antiproliferative activity was …
and screened against two breast cancer cell lines. Considerable antiproliferative activity was …
Novel complex compounds of nickel with 3-(1-phenyl-2, 3-dimethyl-pyrazolone-5) azopentadione-2, 4: synthesis, NBO analysis, reactivity descriptors and in silico and …
S Tahirli, F Aliyeva, H Şenol… - Journal of …, 2024 - Taylor & Francis
A synthesized azo compound based on 4-amino antipyrine and its complexes with Ni (II) in
solution and solid phase is reported. The structures of these compounds have been testified …
solution and solid phase is reported. The structures of these compounds have been testified …
A novel triazole, NMK-T-057, induces autophagic cell death in breast cancer cells by inhibiting γ-secretase–mediated activation of Notch signaling
Notch signaling is reported to be deregulated in several malignancies, including breast, and
the enzyme γ-secretase plays an important role in the activation and nuclear translocation of …
the enzyme γ-secretase plays an important role in the activation and nuclear translocation of …