Virulence factors in coagulase-negative staphylococci

A França, V Gaio, N Lopes, LDR Melo - Pathogens, 2021 - mdpi.com
Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-
associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S …

Emergence of coagulase-negative staphylococci

K Becker, A Both, S Weißelberg… - Expert review of anti …, 2020 - Taylor & Francis
ABSTRACT Introduction: Compared to Staphylococcus aureus, coagulase-negative
staphylococci (CoNS) are characterized by a lower capacity to cause acute, live-threatened …

β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium

JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Niche-specific genome degradation and convergent evolution shaping Staphylococcus aureus adaptation during severe infections

SG Giulieri, R Guérillot, S Duchene, A Hachani… - Elife, 2022 - elifesciences.org
During severe infections, Staphylococcus aureus moves from its colonising sites to blood
and tissues and is exposed to new selective pressures, thus, potentially driving adaptive …

Multidrug resistance (MDR) and collateral sensitivity in bacteria, with special attention to genetic and evolutionary aspects and to the perspectives of antimicrobial …

A Fodor, BA Abate, P Deák, L Fodor, E Gyenge… - Pathogens, 2020 - mdpi.com
Antibiotic poly-resistance (multidrug-, extreme-, and pan-drug resistance) is controlled by
adaptive evolution. Darwinian and Lamarckian interpretations of resistance evolution are …

Comparative genomics of Staphylococcus epidermidis from prosthetic-joint infections and nares highlights genetic traits associated with antimicrobial resistance, not …

E Månsson, T Bech Johannesen… - Microbial …, 2021 - microbiologyresearch.org
There is increased awareness of the worldwide spread of specific epidemic multidrug-
resistant (MDR) lineages of the human commensal Staphylococcus epidermidis. Here, using …

Genomic Insights Into Last-Line Antimicrobial Resistance in Multidrug-Resistant Staphylococcus and Vancomycin-Resistant Enterococcus

AM Turner, JYH Lee, CL Gorrie, BP Howden… - Frontiers in …, 2021 - frontiersin.org
Multidrug-resistant Staphylococcus and vancomycin-resistant Enterococcus (VRE) are
important human pathogens that are resistant to most clinical antibiotics. Treatment options …

Allogenous selection of mutational collateral resistance: old drugs select for new resistance within antibiotic families

F Baquero, JL Martínez, Â Novais… - Frontiers in …, 2021 - frontiersin.org
Allogeneous selection occurs when an antibiotic selects for resistance to more advanced
members of the same family. The mechanisms of allogenous selection are (a) collateral …

The Fusaric Acid Derivative qy17 Inhibits Staphylococcus haemolyticus by Disrupting Biofilm Formation and the Stress Response via Altered Gene Expression

B Wang, CR Song, QY Zhang, PW Wei… - Frontiers in …, 2022 - frontiersin.org
Staphylococcus haemolyticus (S. haemolyticus) is the second most commonly isolated
coagulase-negative staphylococcus (CoNS) in patients with hospital-acquired infections. It …

[HTML][HTML] Pseudomonas aeruginosa responds to altered membrane phospholipid composition by adjusting the production of two-component systems, proteases and …

M Caliskan, G Poschmann, M Gudzuhn… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Membrane protein and phospholipid (PL) composition changes in response to
environmental cues and during infections. To achieve these, bacteria use adaptation …