Lung cancer is the primary cause of mortality in the United States and around the globe.
Therapeutic options for lung cancer treatment include surgery, radiation therapy …

Abstract N 7-methylguanosine (m7G), one of the most prevalent RNA modifications, has
recently attracted significant attention. The m7G modification actively participates in …

Circular RNAs (circRNA) are a class of covalently closed single-stranded RNAs that have
been implicated in cancer progression. Here we identify circNDUFB2 to be downregulated …

Lung cancer is one of the malignant tumors with the highest incidence and mortality in the
world. The overall five-year survival rate of lung cancer is relatively lower than many leading …

Genomic studies of lung adenocarcinoma (LUAD) have advanced our understanding of the
disease's biology and accelerated targeted therapy. However, the proteomic characteristics …

In the United States, lung cancer is the second most common diagnosed cancer and the
leading cause of cancer-related death. Although tobacco smoking is the major risk factor …

Tumor-associated macrophages (TAMs) are major innate immune cells that constitute up to
50% of the cell mass of human tumors. TAMs are highly heterogeneous cells that originate …

Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …

Lung adenocarcinoma (LUAD) remains the most common deadly disease and has a poor
prognosis. Pyroptosis could regulate tumour cell proliferation, invasion, and metastasis …

Abstract MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene
expression by sequential mechanisms such as mRNA breakdown or translational …