[HTML][HTML] LncRNA expression profiles in systemic lupus erythematosus and rheumatoid arthritis: emerging biomarkers and therapeutic targets
H Wu, S Chen, A Li, K Shen, S Wang, S Wang… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are two common
multisystem autoimmune diseases that share, among others, many clinical manifestations …
multisystem autoimmune diseases that share, among others, many clinical manifestations …
Exploring the role of non-coding RNAs in autophagy
As a self-degradative mechanism, macroautophagy/autophagy has a role in the
maintenance of energy homeostasis during critical periods in the development of cells. It …
maintenance of energy homeostasis during critical periods in the development of cells. It …
M6A RNA methylation-mediated RMRP stability renders proliferation and progression of non-small cell lung cancer through regulating TGFBR1/SMAD2/SMAD3 …
H Yin, L Chen, S Piao, Y Wang, Z Li, Y Lin… - Cell Death & …, 2023 - nature.com
Non-small cell lung cancer (NSCLC) has the highest mortality rate among all malignancies
worldwide. The role of long noncoding RNAs (lncRNAs) in the progression of cancers is a …
worldwide. The role of long noncoding RNAs (lncRNAs) in the progression of cancers is a …
[HTML][HTML] Functional interactions between lncRNAs/circRNAs and miRNAs: insights into rheumatoid arthritis
JJ Han, XQ Wang, XA Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases that affect
synovitis, bone, cartilage, and joint. RA leads to bone and cartilage damage and extra …
synovitis, bone, cartilage, and joint. RA leads to bone and cartilage damage and extra …
Molecular mechanism of lncRNAs in pathogenesis and diagnosis of auto-immune diseases, with a special focus on lncRNA-based therapeutic approaches
Autoimmune diseases are a diverse set of conditions defined by organ damage due to
abnormal innate and acquired immune system responses. The pathophysiology of …
abnormal innate and acquired immune system responses. The pathophysiology of …
[HTML][HTML] Small molecule targeting long noncoding RNA GAS5 administered intranasally improves neuronal insulin signaling and decreases neuroinflammation in an …
Shifts in normal aging set stage for neurodegeneration and dementia affecting 1 in 10
adults. The study demonstrates that lncRNA GAS5 is decreased in aged and Alzheimer's …
adults. The study demonstrates that lncRNA GAS5 is decreased in aged and Alzheimer's …
[HTML][HTML] Dysregulation of lncRNAs in rheumatoid arthritis: biomarkers, pathogenesis and potential therapeutic targets
C Miao, L Bai, Y Yang, J Huang - Frontiers in pharmacology, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology, mainly
manifested by persistent abnormal proliferation of fibroblast-like synoviocytes (FLSs) …
manifested by persistent abnormal proliferation of fibroblast-like synoviocytes (FLSs) …
[HTML][HTML] Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations
Immune cell function is critically dependent on precise control over transcriptional output
from the genome. In this respect, integration of environmental signals that regulate gene …
from the genome. In this respect, integration of environmental signals that regulate gene …
[HTML][HTML] A novel lncRNA–protein interaction prediction method based on deep forest with cascade forest structure
X Tian, L Shen, Z Wang, L Zhou, L Peng - Scientific Reports, 2021 - nature.com
Long noncoding RNAs (lncRNAs) regulate many biological processes by interacting with
corresponding RNA-binding proteins. The identification of lncRNA–protein Interactions …
corresponding RNA-binding proteins. The identification of lncRNA–protein Interactions …
[HTML][HTML] The expression of non-coding RNAs and their target molecules in rheumatoid arthritis: a molecular basis for rheumatoid pathogenesis and its potential clinical …
CY Tsai, SC Hsieh, CW Liu, CH Lu, HT Liao… - International journal of …, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a typical autoimmune-mediated rheumatic disease presenting
as a chronic synovitis in the joint. The chronic synovial inflammation is characterized by …
as a chronic synovitis in the joint. The chronic synovial inflammation is characterized by …