The obesity epidemic has intensified efforts to understand the mechanisms controlling
adipose tissue development. Adipose tissue is generally classified as white adipose tissue …

In recent years, injections with filler agents are often used for wrinkle-treatment and soft
tissue augmentation by dermatologists and plastic surgeons. Unfortunately, the ideal filler …

What is boron? The question itself may not seem very significant to many people. Their
introduction to the word “boron” could come as the butt of a joke. Conan O'Brien made jokes …

Lipodystrophy is a medical condition characterized by complete or partial loss of adipose
tissue. Not infrequently, lipodystrophy occurs in combination with pathological accumulation …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …

Proteolytic processing of viral polyproteins is essential for retrovirus infectivity. Retroviral
proteases (PR) become activated during or after assembly of the immature, non-infectious …

CANDLE syndrome (Chronic Atypical Neutrophilic Dermatosis with Lipodystrophy and
Elevated temperature) is a rare, genetic autoinflammatory disease due to abnormal …

Several syndromes manifest as recurrent daily fevers, skin lesions, and multisystem
inflammation. We describe 4 patients with early-onset recurrent fevers, annular violaceous …

In patients infected by HIV, the efficacy of highly active antiretroviral (ARV) therapy through
the blockade of different steps of the retrovirus life cycle is now well established. As HIV is a …

The benefits of long-term antiretroviral therapy (ART) are recognized all over the world with
infected children maturing into adults and HIV infection becoming a chronic illness …