The nephropathy of sickle cell trait and sickle cell disease
KI Ataga, SL Saraf, VK Derebail - Nature Reviews Nephrology, 2022 - nature.com
Sickle cell syndromes, including sickle cell disease (SCD) and sickle cell trait, are
associated with multiple kidney abnormalities. Young patients with SCD have elevated …
associated with multiple kidney abnormalities. Young patients with SCD have elevated …
Advances in the diagnosis and treatment of sickle cell disease
AM Brandow, RI Liem - Journal of Hematology & Oncology, 2022 - Springer
Sickle cell disease (SCD), which affects approximately 100,000 individuals in the USA and
more than 3 million worldwide, is caused by mutations in the βb globin gene that result in …
more than 3 million worldwide, is caused by mutations in the βb globin gene that result in …
Natural history and variability in albuminuria in pediatric and murine sickle cell anemia
It is critical to characterize the natural history of albuminuria in patients with sickle cell
anemia (SCA); however, these data are currently lacking and affecting evidence-based …
anemia (SCA); however, these data are currently lacking and affecting evidence-based …
[HTML][HTML] Sickle cell nephropathy: A review of novel biomarkers and their potential roles in early detection of renal involvement
OY Safdar, RM Baghdadi, SA Alahmadi… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Whether the underlying mutations are homozygous, heterozygous, or co-inherited with other
hemoglobinopathies, sickle cell disease is known to afflict the kidneys, leading to the clinical …
hemoglobinopathies, sickle cell disease is known to afflict the kidneys, leading to the clinical …
[HTML][HTML] Voxelotor and Albuminuria in Adults with Sickle Cell Anemia
J Han, RE Molokie, F Hussain, F Njoku… - British journal of …, 2022 - ncbi.nlm.nih.gov
The kidneys are among the most commonly affected organ systems in patients with sickle
cell anemia (SCA) and an estimated 15% of deaths in patients with SCA are attributed to …
cell anemia (SCA) and an estimated 15% of deaths in patients with SCA are attributed to …
Nontargeted Plasma Proteomic Analysis of Renal Disease and Pulmonary Hypertension in Patients with Sickle Cell Disease
ME Garrett, MW Foster, MJ Telen… - Journal of Proteome …, 2024 - ACS Publications
Sickle cell disease (SCD) is characterized by red blood cell sickling, vaso-occlusion,
hemolytic anemia, damage to multiple organ systems, and, as a result, shortened life …
hemolytic anemia, damage to multiple organ systems, and, as a result, shortened life …
Longitudinal study of glomerular hyperfiltration and normalization of estimated glomerular filtration in adults with sickle cell disease
VK Derebail, Q Zhou, EJ Ciccone… - British journal of …, 2021 - Wiley Online Library
Glomerular hyperfiltration is common in sickle cell disease (SCD) and precedes proteinuria
and declining kidney function. We evaluated hyperfiltration in SCD patients and its …
and declining kidney function. We evaluated hyperfiltration in SCD patients and its …
Sickle cell disease and kidney
P Amarapurkar, L Roberts, J Navarrete… - Advances in Chronic …, 2022 - Elsevier
Sickle cell disease causes several kidney manifestations. They include defects in urine
concentration, impaired handling of potassium and hydrogen ion, albuminuria, acute kidney …
concentration, impaired handling of potassium and hydrogen ion, albuminuria, acute kidney …
Plasma levels of E‐selectin are associated with retinopathy in sickle cell disease
I Agouti, E Masson, A Loundou, E Jean… - European Journal of …, 2023 - Wiley Online Library
Background The vascular endothelium is markedly disrupted in sickle cell disease (SCD)
and is the converging cascade of the complex pathophysiologic processes linked to sickle …
and is the converging cascade of the complex pathophysiologic processes linked to sickle …
Impact of pre‐eclampsia on renal outcome in sickle cell disease patients
I Boudhabhay, E Boutin, P Bartolucci… - British journal of …, 2021 - Wiley Online Library
The long‐term consequences of pre‐eclampsia (PrE) for renal function have never been
determined in patients with sickle cell disease (SCD). Between 2008 and 2015, we …
determined in patients with sickle cell disease (SCD). Between 2008 and 2015, we …