Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases

E Plazas, DR Muñoz - Pharmacological Research, 2022 - Elsevier
Complex diseases such as neurodegenerative disorders and cancer constitute a growing
public health problem due to the rising incidence and lack in effective therapies. Since …

Exploring allocryptopine as a neuroprotective agent against oxidative stress-induced neural apoptosis via Akt/GSK-3β/tau pathway modulation

B Aslim, SN Dolanbay, SS Baran - Computational Biology and Chemistry, 2024 - Elsevier
Alzheimer's disease (AD) is characterized by neuronal loss due to hyperphosphorylated
proteins induced by oxidative stress. AD remains a formidable challenge in the medical field …

New Berberine Conjugates with Self-Assembly and Improved Antioxidant/Neuroprotection Properties: Effect of the Anchored Part on CMC, Shape and Size of the …

Z Afroozandeh, P Rashidi Ranjbar, M Khoobi… - Journal of Cluster …, 2024 - Springer
Berberine (Ber) as a natural isoquinoline alkaloid, with a wide range of biological activities,
mainly suffers from low bioavailability, decreasing its therapeutic efficacy. In this study, two …

Neurotrophic Natural Products

Y Fukuyama, M Kubo, K Harada - Neurotrophic Natural Products, 2024 - Springer
Abstract Neurotrophins (NGF, BDNF, NT3, NT4) can decrease cell death, induce
differentiation, as well as sustain the structure and function of neurons, which make them …

[PDF][PDF] NEUROPROTECTIVE EFFECTS OF THYMOQUINONE-RICH FRACTION AND THYMOQUINONE NANOEMULSIONS IN SPORADIC ALZHEIMER'S DISEASE …

NB ISMAIL - 2019 - core.ac.uk
UNIVERSITI PUTRA MALAYSIA NEUROPROTECTIVE EFFECTS OF THYMOQUINONE-RICH
FRACTION AND THYMOQUINONE NANOEMULSIONS IN SPORADIC ALZHE Page 1 …