Initiating and maintaining optimal immune responses requires high levels of protein
synthesis, folding, modification and trafficking in leukocytes, which are processes …

Abstract Purpose of Review Non-alcoholic fatty liver disease (NAFLD) is one of the most
common causes of chronic liver disease with rising prevalence worldwide. Herein, we …

M2-tumor associated macrophages (TAMs) play an important role in tumor genesis,
progression, and metastasis, and repolarizing M2-TAMs to immune-promoting M1 type is …

Osteopontin characterizes bile duct–associated macrophages a... : Hepatology Osteopontin
characterizes bile duct–associated macrophages and correlates with liver fibrosis severity in …

Chronic liver diseases from varying etiologies generally lead to liver fibrosis and cirrhosis.
Among them, non-alcoholic fatty liver disease (NAFLD) affects roughly one-quarter of the …

The incidence of nonalcoholic fatty liver disease (NAFLD) is on the rise, mirroring a global
surge in diabetes and metabolic syndrome, as its major leading causes. NAFLD represents …

Chronic liver disease (CLD) is a growing health concern which accounts for two million
deaths per year. Obesity, alcohol overconsumption, and progressive cholestasis are …

The P2Y12 receptor is an adenosine diphosphate responsive G protein-coupled receptor
expressed on the surface of platelets and is the pharmacologic target of several anti …

Abstract Background The Metabolic reprogramming of tumor cells plays a vital role in the
progression of hepatocellular carcinoma. Organic cation/carnitine transporter 2 (OCTN2), a …

Metabolic and personalized interventions in cancer treatment require a better understanding
of the relationship between the induction of cell death and metabolism. Consequently, we …