The sympathetic nervous system in development and disease

E Scott-Solomon, E Boehm, R Kuruvilla - Nature Reviews …, 2021 - nature.com
The sympathetic nervous system prepares the body for 'fight or flight'responses and
maintains homeostasis during daily activities such as exercise, eating a meal or regulation …

Sympathetic and sensory-motor nerves in peripheral small arteries

C Aalkjær, H Nilsson, JGR De Mey - Physiological reviews, 2021 - journals.physiology.org
Small arteries, which play important roles in controlling blood flow, blood pressure, and
capillary pressure, are under nervous influence. Their innervation is predominantly …

Imaging the mammary gland and mammary tumours in 3D: optical tissue clearing and immunofluorescence methods

B Lloyd-Lewis, FM Davis, OB Harris, JR Hitchcock… - Breast Cancer …, 2016 - Springer
Background High-resolution 3D imaging of intact tissue facilitates cellular and subcellular
analyses of complex structures within their native environment. However, difficulties …

Endothelin and the heart in health and diseases

T Miyauchi, S Sakai - Peptides, 2019 - Elsevier
Abstract Endothelin-1 (ET-1), a 21-amino acid peptide, was initially identified in 1988 as a
potent vasoconstrictor and pressor substance isolated from the culture supernatant of …

Local sympathetic denervation attenuates myocardial inflammation and improves cardiac function after myocardial infarction in mice

KA Ziegler, A Ahles, T Wille, J Kerler… - Cardiovascular …, 2018 - academic.oup.com
Aims Cardiac inflammation has been suggested to be regulated by the sympathetic nervous
system (SNS). However, due to the lack of methodology to surgically eliminate the …

Sympathetic tales: subdivisons of the autonomic nervous system and the impact of developmental studies

U Ernsberger, H Rohrer - Neural Development, 2018 - Springer
Remarkable progress in a range of biomedical disciplines has promoted the understanding
of the cellular components of the autonomic nervous system and their differentiation during …

Coronary artery development: progenitor cells and differentiation pathways

B Sharma, A Chang, K Red-Horse - Annual review of physiology, 2017 - annualreviews.org
Coronary artery disease (CAD) is the number one cause of death worldwide and involves
the accumulation of plaques within the artery wall that can occlude blood flow to the heart …

Cardiac innervation and the autonomic nervous system in SCD

W Huang, N Boyle, M Vaseghi - Cardiac electrophysiology …, 2017 - pmc.ncbi.nlm.nih.gov
Neural remodeling in the autonomic nervous system contributes significantly to sudden
cardiac death. The fabric of cardiac excitability and propagation are controlled by autonomic …

Unlocking cardiomyocyte renewal potential for myocardial regeneration therapy

M Mehdipour, S Park, GN Huang - Journal of molecular and cellular …, 2023 - Elsevier
Cardiovascular disease remains the leading cause of mortality worldwide. Cardiomyocytes
are irreversibly lost due to cardiac ischemia secondary to disease. This leads to increased …

Quantification of sympathetic hyperinnervation and denervation after myocardial infarction by three-dimensional assessment of the cardiac sympathetic network in …

T Yokoyama, JK Lee, K Miwa, T Opthof, S Tomoyama… - PloS one, 2017 - journals.plos.org
Background The sympathetic nervous system is critical in maintaining the normal
physiological function of the heart. Its dysfunction in pathological states may exacerbate the …